Results 61 to 70 of about 27,196 (188)

Citrullination and Deamidation in Type 1 Diabetes: Linking Beta Cell Stress to Neoantigen‐Driven Autoimmunity

open access: yesImmunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Citrullination and deamidation are post‐translational modifications (PTMs) increasingly recognized as important contributors to neoepitope formation in type 1 diabetes (T1D). Under inflammatory and endoplasmic reticulum stress conditions, beta cells activate calcium‐dependent peptidylarginine deiminase and transglutaminase enzymes, leading to ...
Aïsha Callebaut   +4 more
wiley   +1 more source

Variability and genetic differentiation among Anopheles (Ano.) intermedius Chagas, 1908 and Anopheles (Ano.) mattogrossensis Lutz & Neiva, 1911 (Diptera: Culicidae) from the Brazilian Amazon

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Anopheles (Anopheles) intermedius and Anopheles (Ano.) mattogrossensis are Brazilian anopheline species belonging to the scarcely studied Anopheles subgenus. Few studies have been done on the genetic differentiation of these species.
Joselita Maria Mendes dos Santos   +3 more
doaj   +1 more source

The Role of Gut Microbiota in Liver Regeneration After Partial Hepatectomy: New Evidence From Animal and Human Studies

open access: yesThe FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Partial hepatectomy (PH) reshapes gut microbiota composition, resulting in the release of microbial metabolites and components, including short chain fatty acids (SCFAs)/β‐hydroxybutyric acid (BHB), bacterial DNA and extracellular vesicles (EVs), bile acids (deoxycholic acid, DCA), and aminobenzoate degradation products.
Roberto Loi   +3 more
wiley   +1 more source

Distribution, ecology, life history, genetic variation, and risk of extinction of nonhuman primates from Costa Rica

open access: yesRevista de Biología Tropical, 2004
We examined the association between geographic distribution, ecological traits, life history, genetic diversity, and risk of extinction in nonhuman primate species from Costa Rica.
María E Zaldívar   +6 more
doaj  

Application of genetic markers in seed testing and plant breeding [PDF]

open access: yesRatarstvo i Povrtarstvo, 2010
Genetic markers have been used at Institute of Field and Vegetable Crops in Novi Sad for a number of years, both for seed quality control and for research purposes.
Nikolić Zorica
doaj  

Isozyme analysis of Taenia solium isolates from Mexico and Colombia

open access: yesMemorias do Instituto Oswaldo Cruz, 2003
Mexican and Colombian Taenia solium cysticerci and some species of Taenia adults were assayed using cellulose acetate electrophoresis to distinguish between isolates.
Pablo Maravilla   +4 more
doaj   +1 more source

A Proposed Complete‐Cycle Mechanism for Conversion of N2 to NH3 by Mo‐Nitrogenase

open access: yesChemBioChem, Volume 27, Issue 14, 29 July 2026.
How does the enzyme nitrogenase convert N2 to NH3 under ambient conditions? Here I describe a proposed complete cycle of the chemical mechanism, with computed energy profiles and kinetic barriers for a sequence of 31 reaction steps, encompassing 40 intermediates. How does the enzyme nitrogenase convert N2 to NH3 under ambient conditions?
Ian Dance
wiley   +1 more source

Recent developments in biochemical characterization of Vitis vinifera L. varieties in Hungary

open access: yesInternational Journal of Horticultural Science, 2002
Isoelectric focusing is an effective and well reproducible method to provide information for identification of various plant species and clones if breeding or other genetic modification(s) for a given species are reflected in changes of an isozyme ...
É. Stefanovits-Bányai   +4 more
doaj   +1 more source

Sultams as Dual Inhibitors of Human Carbonic Anhydrase and Thioredoxin Reductase

open access: yesChemMedChem, Volume 21, Issue 14, 29 July 2026.
A series of sultam‐based N‐acyl derivatives with potential applications as dual TrxR1 and CA inhibitors were synthesized and evaluated. TrxR1 screening identified several active compounds, with inhibitory potency influenced by the type and orientation of substituents.
Aleksandrs Pustenko   +8 more
wiley   +1 more source

Investigating the Inhibitory Properties of Diazo and Pyrazole‐Carboxamide‐Linked Benzenesulfonamides Against Carbonic Anhydrase Isoforms I, II, IX, and XII

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
Hybrid diazo‐ and pyrazole‐carboxamide benzenesulfonamides emerge as highly potent and selective inhibitors of tumor‐associated carbonic anhydrases. A 3,4‐dichloro‐substituted derivative achieves sub‐2 nM inhibition of hCA IX and displays promising anticancer activity, revealing a valuable scaffold for the development of next‐generation cancer‐targeted
Suleyman Akocak   +8 more
wiley   +1 more source

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