Results 71 to 80 of about 35,897 (231)

Mechanism of Phosphorylation-Induced Activation of Phospholipase C-γ Isozymes

open access: yes, 2010
Phospholipase C (PLC) isozymes regulate numerous cellular events including fertilization, proliferation, differentiation, and chemotaxis. PLCs hydrolyze phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) into the second messengers diacylglycerol (DAG)
Gresset, Aurelie M.
core   +1 more source

Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Brice Beauvais   +5 more
wiley   +1 more source

Genetic variation within and among naturally regenerating populations of alder (Alnus glutinosa)

open access: yesActa Societatis Botanicorum Poloniae, 2011
To assess the inter- and intrapopulation genetic variation in the filial generation (F1) of alder (Alnus glutinosa (L.) Gaertn.), 11 naturally regenerated populations were analysed. Their parental populations (P), represent the whole Polish territory and
Leon Mejnartowicz
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

ISOZYME HISTOCHEMISTRY: THE DISPLAY OF SELECTIVE LACTATE DEHYDROGENASE ISOZYMES IN SECTIONS OF SKELETAL MUSCLE

open access: yes, 1964
The addition of chemical agents to the standard lactate dehydrogenase (LDH) incubating medium permits the histochemical display of selective LDH isozymes.
W. KING ENGEL, IRWIN A. BRODY
core   +1 more source

Analysis of Two New Flavonoid Glycosides From Zanha golungensis Hiern With COX Inhibition Activity: Structural Elucidation, DFT Calculations, In Vitro and Molecular Docking Assessment

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
Zanha golungensis contains phenolic compounds amongst which are two previously undescribed flavonoid glycosides as shown in this study. The constituents of this plant exhibit anti‐inflammatory activity by inhibiting cyclooxygenases (COX‐1 and COX‐2).
Jean Zeuikena   +7 more
wiley   +1 more source

Identification of ADP-ribosylation site in human glutamate dehydrogenase isozymes

open access: yes, 2005
When the influence of ADP-ribosylation on the activities of the purified human glutamate dehydrogenase isozymes (hGDH1 and hGDH2) was measured in the presence of 100μM NAD+ for 60min, hGDH isozymes were inhibited by up to 75%.
Seung-Ju Yang   +11 more
core   +1 more source

Multi‐Omics Analyses Elucidate the Venom Components of the Wasp Vespa mandarinia

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
The wasp Vespa mandarinia was widely reared in Yunnan province. The venom was responsible for their aggressive behavior. Tweety proteases, hyaluronidase, venom dipeptidyl peptidase 4, and phospholipase A1 and A2 isozyme were identified. In addition, organic heterocyclic compounds, organic acids, and derivatives were found.
Yuan‐Chong Shi   +4 more
wiley   +1 more source

Population genetics of the pink snail Strombus gigas in the Yucatan Peninsula:Implications for its management and fishery

open access: yesCiencias Marinas, 2005
The genetic population structure of the pink snail Strombus gigas in the Yucatan Peninsula, Mexico, was determined by isozyme expression in polyacrylamide gels.
Jorge A Tello-Cetina   +2 more
doaj   +1 more source

Induction of Apoptosis in MCF‐7 Breast Cancer Cells by Selenium Nanoparticles Synthesized With Laccase Enzyme Isolated From Pleurotus Floridanus

open access: yeseFood, Volume 7, Issue 3, June 2026.
This study showed the first successful synthesis of selenium nanoparticles (SeNPs) using laccase purified from Pleurotus floridanus, offering an eco‐friendly and biocompatible replacement to conventional chemical methods. The biosynthesized SeNPs exhibited significant antiproliferative effects on MCF‐7 breast cancer cells, with cell cycle analysis ...
Shenbhagaraman Ramalingam   +7 more
wiley   +1 more source

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