Results 31 to 40 of about 35,897 (231)

Selective Usage of Isozymes for Stress Response

open access: yes, 2018
Isozymes are enzymes with similar sequences that catalyze the same reaction in a given species. In Saccharomyces cerevisiae, most isozymes have major isoforms with high expression levels and minor isoforms with little expression under normal growth ...
Yugang Zhang (1579516)   +3 more
core   +1 more source

A new continuous cell line from the mosquito Psorophora confinnis (Diptera: Culicidae) and its susceptibility to infections with some arboviruses

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
A new cell line, PC-0199-BR, was established from embryonated eggs of the mosquito Psorophora confinnis. To date (September 2000) it has had 62 continuous passages.
Felio J Bello   +6 more
doaj   +1 more source

Modulation of Cell Components and Specific Isoforms of Antioxidant Enzymes in Safflower Under Water Stress and Recovery [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2021
Drought tolerance represents a growing threat to crop productivity. Safflower is one of the major oilseed crop enriched with various nourishing elements.
Thippeswamy M.   +3 more
doaj  

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Variabilidade Genética em Populações Naturais de Cassia grandis L. f.

open access: yesFloresta e Ambiente, 2018
RESUMO O delineamento de estratégias para a conservação genética de uma espécie requer o conhecimento de aspectos ecológicos e genéticos de suas populações.
Itamara Bomfim Gois   +2 more
doaj   +1 more source

Design and synthesis of diazine-based panobinostat analogues for HDAC8 inhibition

open access: yesBeilstein Journal of Organic Chemistry, 2020
Guided by computational analysis, herein we report the design, synthesis and evaluation of four novel diazine-based histone deacetylase inhibitors (HDACis). The targets of interest (TOI) are analogues of panobinostat, one of the most potent and versatile
Sivaraman Balasubramaniam   +8 more
doaj   +1 more source

Induction of cytochrome P450 2C9 and P‐glycoprotein activity by antiseizure medications: A systematic review and network meta‐analysis

open access: yesEpileptic Disorders, EarlyView.
Abstract Objectives Antiseizure medications (ASMs) can induce the activity of drug‐metabolizing enzymes and drug transporters, including cytochrome P450 (CYP)2C9 and P‐glycoprotein (P‐gp). Our objective was to comparatively assess the effects of ASMs on exposure to clinical CYP2C9 and P‐gp substrates.
Hagar Cohen   +4 more
wiley   +1 more source

Rhodanese isozymes in human tissues

open access: yes, 1988
An investigation of a range of tissue homogenates by various electrophoretic methods, followed by staining for specific enzyme activity, has revealed a series of isozymes of human rhodanese.
WHITEHOUSE D. B.   +3 more
core   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Variability and genetic differentiation among Anopheles (Ano.) intermedius Chagas, 1908 and Anopheles (Ano.) mattogrossensis Lutz & Neiva, 1911 (Diptera: Culicidae) from the Brazilian Amazon

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Anopheles (Anopheles) intermedius and Anopheles (Ano.) mattogrossensis are Brazilian anopheline species belonging to the scarcely studied Anopheles subgenus. Few studies have been done on the genetic differentiation of these species.
Joselita Maria Mendes dos Santos   +3 more
doaj   +1 more source

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