Results 61 to 70 of about 34,055,496 (229)

Vol. 53 - 1 - 2021 - Special Issue: Half-century spreading veterinary sciences

open access: yes, 2021
Special Issue: Half-century spreading veterinary ...
Issue, January
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

LITES, Volume 1, Issue 2

open access: yes, 2014
LITES, Volume 1, Issue

core   +1 more source

Reviewers in this issue Vol.1(1)

open access: yesDelta Medical College Journal, 2012
DOI: http://dx.doi.org/10.3329/dmcj.v1i1.14974 Delta Med Col J.
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Dagstuhl Manifestos, Volume 1, Issue 1, January - December 2011, Complete Issue

open access: yes, 2012
oai:drops-oai.dagstuhl.de:3449Dagstuhl Manifestos, Volume 1, Issue 1, January - December 2011, Complete ...

core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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