Results 111 to 120 of about 5,248,567 (304)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Minutes: Senate Disabilities Issues Committee: September 13, 1999
, 1999 University of Minnesota: Senate Disabilities Issues Committee. (1999). Minutes: Senate Disabilities Issues Committee: September 13, 1999.
University of Minnesota: Senate Disabilities Issues Committee
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Minutes: Senate Disabilities Issues Committee: June 24, 2020
, 2020 University of Minnesota: Senate Disabilities Issues Committee. (2020). Minutes: Senate Disabilities Issues Committee: June 24, 2020.
University of Minnesota: Senate Disabilities Issues Committee
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Фундаментальная и клиническая медицинаAim. To validate ECFC culture as a candidate culture for vascular tissue engineering using comparative analysis of the proteomic and gene expression profiles in comparison with cultures of human umbilical vein endothelial cells (HUVEC) and human coronary
M. Yu. Khanova +5 more
doaj +1 more source
Stop the bomb: An appeal to the reason of the American people
, 1953 https://stars.library.ucf.edu/prism/1833/thumbnail ...
Contemporary Issues
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Minutes: Senate Disabilities Issues Committee: November 15, 2006
, 2006 Disability Services Update, Disabled Students Cultural Center Update, Latex Update, Mental Health Task Force UpdateUniversity of Minnesota: Senate Disabilities Issues Committee. (2006).
University of Minnesota: Senate Disabilities Issues Committee
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Minutes: Senate Disabilities Issues Committee: January 28, 2020
, 2020 University of Minnesota: Senate Disabilities Issues Committee. (2020). Minutes: Senate Disabilities Issues Committee: January 28, 2020.
University of Minnesota: Senate Disabilities Issues Committee
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source