Results 161 to 170 of about 5,248,567 (304)

Minutes: Senate Disabilities Issues Committee: March 22, 2017

open access: yes, 2017
University of Minnesota: Senate Disabilities Issues Committee. (2017). Minutes: Senate Disabilities Issues Committee: March 22, 2017.
University of Minnesota: Senate Disabilities Issues Committee
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Japan essential medicine list and medicine supply issues: a cross-sectional study. [PDF]

open access: yesJ Pharm Policy Pract
Heredia C   +3 more
europepmc   +1 more source

Minutes: Senate Disabilities Issues Committee: October 23, 2013

open access: yes, 2013
University of Minnesota: Senate Disabilities Issues Committee. (2013). Minutes: Senate Disabilities Issues Committee: October 23, 2013.
University of Minnesota: Senate Disabilities Issues Committee
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Trends in EU regulatory assessment of oncology medicines. [PDF]

open access: yesESMO Open
Pabsch T   +4 more
europepmc   +1 more source

Minutes: Senate Disabilities Issues Committee: November 18, 2015

open access: yes, 2015
University of Minnesota: Senate Disabilities Issues Committee. (2015). Minutes: Senate Disabilities Issues Committee: November 18, 2015.
University of Minnesota: Senate Disabilities Issues Committee
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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