Results 231 to 240 of about 5,248,567 (304)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Identifying the Challenges of Prehospital Emergency Centers in Providing Care in Wartime and Proposing Strategic Solutions: A Qualitative Study. [PDF]

Health Sci Rep
Miadfar J, Arab MA, Nourisari H, Sarwar M, Dehghanpour R, Bijani M.   +5 more
europepmc   +1 more source

Expression of Concern: Economic policy uncertainty, intra-industry trade, and China's mechanical and electrical product exports. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

IN THIS ISSUE

Complementary Therapies in Medicine, 2002
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Interrogating the "Us" Versus "Them" Dichotomy in Technology Research with Older Adults. [PDF]

Proc SIGCHI Conf Hum Factor Comput Syst
Lazar A, Carpio E, Hu R, Barnett B, Tesfatsion K, Erete S.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Why We Don't Use Guest Editors: A Publisher's Perspective. [PDF]

Blockchain Healthc Today
Cenaj T.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Methodological Issues Related to the Reported Association of A Body Shape Index With Abdominal Aortic Calcification in Patients With Hypertension. [PDF]

Clin Cardiol
Shahab L, Khan SH, Zain JK.
europepmc   +1 more source