Results 41 to 50 of about 10,645 (216)

Non‐Invasive Assessment of Perineural Invasion Density: A Novel Marker for Prognosis and Treatment Stratification in Prostate Cancer

Advanced Science, EarlyView.
This study establishes perineural invasion density (PNID) as a superior prognostic marker in prostate cancer, outperforming conventional perineural invasion in predicting biochemical recurrence and radiographic progression. Concurrent β–blocker use is associated with favorable outcomes exclusively in High–PNID patients. An MRI–based deep learning model
Bohao Liu, Long Zhang, Weian Zhu, Meng Yang, Xiang Liu, Xiaoyang Li, Peng Qin, Zhengxu Lin, Qian Cai, Jiayu Zheng, Xiao Zhao, Chen Zou, Xuan Wen, Longhao Xu, Daqin Wu, Lin Zhang, Cuilian Zhang, Kaiwen Li, Chunhui Wang, Wenlong Zhong, Yun Luo   +20 more
wiley   +1 more source

Risk Stratification of Prostate Imaging Reporting and Data System (PI‐RADS 3) Lesions in the Peripheral and Transition Zones Using Clinical and Quantitative MRI Markers

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Prostate Imaging Reporting and Data System (PI‐RADS) 3 lesions often undergo biopsy despite a low positive predictive value (< 25%) for clinically significant prostate cancer (csPCa), defined as International Society of Urological Pathology (ISUP) Grade Group ≥ 2.
Tejinder Kaur, Reve Chahine, Nicole Seiberlich, Hero Hussain, Shane Wells, Vikas Gulani, Yun Jiang   +6 more
wiley   +1 more source

Prognostic Value of the New Prostate Cancer International Society of Urological Pathology Grade Groups

Frontiers in Medicine, 2017
Gleason grading is the best independent predictor for prostate cancer (PCa) progression. Recently, a new PCa grading system has been introduced by the International Society of Urological Pathology (ISUP) and is recommended by the World Health ...
Anne Offermann, Silke Hohensteiner, Christiane Kuempers, Julika Ribbat-Idel, Felix Schneider, Finn Becker, Marie Christine Hupe, Stefan Duensing, Axel S. Merseburger, Jutta Kirfel, Markus Reischl, Verena Lubczyk, Rainer Kuefer, Sven Perner   +13 more
doaj   +1 more source

Dosimetry, Toxicity and Stability Associated With a Hyaluronic Acid‐Based Prostate‐Rectal Spacing Device During Prostate Radiation Therapy: A Retrospective Comparative Analysis

Journal of Medical Radiation Sciences, EarlyView.
Rectal spacers composed of stabilised hyaluronic acid facilitated a favourable toxicity profile compared to no spacing during prostate radiation therapy. Acute GI toxicity (grade ≥ 1) was lower in the spacer cohort (23.5% vs. 48.0%; odds ratio = 0.33, p = 0.05) with grade ≥ 2 toxicity substantially lower (2.9% vs. 20.0%).
Fadila Najem, Bridget Smith, Sary Chen, Lucinda Wood, Asmaa El‐Heneidy, Lloyd Smyth, Hodo Haxhimolla, Pat Bowden   +7 more
wiley   +1 more source

A two‐stage model for precise identification and Gleason grading of clinically significant prostate cancer: a hybrid approach

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 93-105, March 2025.
This study developed a two‐stage model using radiomics‐based multiparametric MRI and clinical indicators to help identify and grade clinically significant prostate cancer. The model showed promising levels of diagnostic accuracy and predictive performance.
Yuyan Zou, Xuechun Wang, Fen Ma, Xulun Liu, Chunyue Jiao, Zhen Kang, Jingjing Cui, Yang Zhang, Yan Xie, Lei Chen, Ronghua Tian   +10 more
wiley   +1 more source

Forest plots showing the odds ratios with 95% confidence intervals for the risk of ISUP grade specific outcomes in biopsy.

, 2019
The reference level is a man with PSA of 2–3 ng/mL and age group 50–54 years and the plot shows the odds ratios comparing these groups to men in the reference level group. A: Overall ISUP grade.
Johan Lindberg (18863), Lars Egevad (124325), Mark Clements (387864), Martin Eklund (91839), Markus Aly (523056), Henrik Grönberg (122512), Tobias Nordström (5997566), Thorgerdur Palsdottir (6837641)   +7 more
core   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang, Zhi‐Yan Jin, Min‐Ying Lydia Su   +2 more
wiley   +1 more source

PSA AND ITS RELATION TOTHE DEGREE OF DIFFERENTIATION OF PROSTATE CANCER

Trakia Journal of Sciences
INTRODUCTION: Prostate-specific antigen (PSA) and Gleason score are two of the most important characteristics of prostate cancer. Their complex and ambiguous connection prompted us to examine it in a series of patients operated in our clinic.
B. Lazarov
doaj   +1 more source

Test Suite Migration Experiences for B-ISUP and B-MTP [PDF]

, 1998
It is well known that the development of ATSs and ETSs is time and cost intensive. This contribution provides practical experiences and results gained from a test suite development project in the context of today’s ATM protocols. In particular we discuss the problems and effort to develop and execute the BISUP and MTP test suites within B-ISDN based on
Claude Desroches, Mang Li, Stephan Pietsch, Axel Rennoch, Ina Schieferdecker, Theofanis Vassiliou-Gioles   +5 more
openaire   +2 more sources

Subsequent Detection of Clinically Significant Prostate Cancer After Suspicious MRI and an Initial Biopsy Negative for csPCa: A Longitudinal Subgroup Analysis of the MULTIPROS Trial

The Prostate, EarlyView.
ABSTRACT Background Management after suspicious multiparametric MRI (mpMRI; PI‐RADS ≥ 3) and an initial biopsy negative for clinically significant prostate cancer (csPCa) remains uncertain. We described the frequency of subsequent csPCa detection and explored baseline factors. Methods This post hoc longitudinal analysis of MULTIPROS trial data included
Wafa D. Aloufi, Magdalena Szewczyk‐Bieda, Ghulam Nabi, Xinyu Zhang, Yilong Zhang, Cheng Wei, Luigi Manfredi   +6 more
wiley   +1 more source