Active surveillance should not be routinely considered in ISUP grade group 2 prostate cancer [PDF]
Active surveillance has been proposed as a therapeutic option in selected intermediate risk patients with biopsy grade group 2 prostate cancer. However, its oncologic safety in this setting is debated.
Giorgio Gandaglia +5 more
doaj +2 more sources
Clinicopathological factors associated with pathological upgrading from biopsy to prostatectomy in patients with ISUP grade group ≤2 prostate cancer [PDF]
We performed this study to investigate pathological upgrading from biopsy to prostatectomy and clinicopathological factors associated with grade group (GG) upgrading in patients with International Society of Urological Pathology (ISUP) GG 1 and 2 ...
Xing Li +5 more
doaj +2 more sources
The value of multiparametric magnetic resonance imaging in the prognostic judgment of prostate cancer [PDF]
Both the Gleason grading system, which assesses prostate cancer aggressiveness, and the D’Amico risk classification, which predicts the likelihood of tumor recurrence, require post-surgical data to provide results.
Yanyan Yu +8 more
doaj +2 more sources
Is MRI/US-guided fusion biopsy ready to replace systematic biopsy in detecting clinically significant prostate carcinoma? – a retrospective study [PDF]
Background This study aims to evaluate whether MRI-US-guided FB leads to improved diagnostic accuracy compared to SB and whether SB remains necessary for the detection of csPCa, further assessing whether the TP or TR biopsy approach influences outcomes ...
Alexandra Ökrösi +4 more
doaj +2 more sources
Omission of contralateral biopsies in unilateral MRI‐suspicious prostate cancer has minimal impact on clinical risk assessment [PDF]
Background and Objective MRI‐targeted biopsies (TBx) combined with systematic biopsies (SBx) have traditionally been recommended for patients with unilateral MRI‐suspicious prostate cancer (PCa) lesions.
Stijn M. van denBosch +9 more
doaj +2 more sources
Noninvasive preoperative risk stratification of prostate cancer via a foundational model based deep learning with PSMA PET/CT [PDF]
Purpose To develop and internally validate a PSMA PET/CT–centric deep-learning framework based on using a foundational model for noninvasive preoperative risk stratification of prostate cancer at the ISUP Grade Group (GG) 1–2 vs.
Linjie Bian +6 more
doaj +2 more sources
Performance of Ga-68 PSMA PET/CT for diagnosis and grading of local prostate cancer
Background: We aimed to evaluate the utility of prostate-specific membrane antigen (PSMA) PET/CT for the detection of local disease within the prostate.
Timothy N. Kwan +5 more
doaj +1 more source
ObjectiveTo investigate the prognostic value of local therapy (LT) in cN1M0 prostate cancer (PCa).MethodsPatients diagnosed with cN1M0 PCa were extracted from the surveillance, epidemiology, and end results (SEER) database.
Feng Qi +5 more
doaj +1 more source
Gleason grading is the best independent predictor for prostate cancer (PCa) progression. Recently, a new PCa grading system has been introduced by the International Society of Urological Pathology (ISUP) and is recommended by the World Health ...
Anne Offermann +13 more
doaj +1 more source
Objective: To investigate the relationship between the new International Society of Urological Pathology (ISUP) grading system, biochemical recurrence (BCR), clinical progression (CP) and cancer related death (CRD) after open radical prostatectomy (RP ...
Daimantas Milonas +9 more
doaj +1 more source

