Results 71 to 80 of about 39,203,027 (304)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Business-driven IT Management [PDF]
, 2009 Business-driven IT management (BDIM) aims at ensuring successful alignment of business and IT through thorough understanding of the impact of IT on business results, and vice versa.
Bartolini, Claudio
core
IT Service Management Implementation Strategy of Resource Pool Environment
Dianxin kexue, 2012 This paper summarizes the IT service management implementation present situation, analyzes the construction and operation of the cloud computing environment resource pool for the IT service management system bringing challenges, and puts forward the ...
Chunhua Chen +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Measuring the performance of IT service management
, 2011 Despite the appeal and the tremendous potential to realise benefits, the implementation of IT Service Management (ITSM) initiatives is hindered by the difficulty in quantifying benefits and measuring performance.
Cater-Steel, Aileen +2 more
core +1 more source
Service Management and Tourism
, 2018 The world economy is dominated by the service sector, with the traditional ‘primary’ and ‘secondary’ industries (of agriculture, raw materials and manufacturing) being overtaken in the past few decades. More recently, these changes are even more profound, with advances in information technology, mobile technology and big data providing revolutionary ...
Solnet, David, Golubovskaya, Maria
openaire +3 more sources
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Managing IT-service performance and IT-service quality
, 2008 The growing complexity in the management of ITservices is an important aspect for IT-managers. Due to outsourcing and the development of the increasing modularization of IT-services and IT-infrastructures there is a rising challenge for companies to ...
It-service Cachet
core
A Performance Measurement Framework for IT Service Management
A framework and associated metrics and measures that can be used to measure the performance of IT service management with an accompanying contingency theory of IT service ...
Gacenga, Francis
core +1 more source