Results 51 to 60 of about 34,312,534 (257)
АНАЛИЗ ПРОБЛЕМНЫХ МОМЕНТОВ ПРИ ВНЕДРЕНИИ ПОДХОДА ITSM В ОРГАНИЗАЦИЯХ
Cifra: Информационные технологии и телекоммуникацииВ статье обозначена проблема внедрения ITSM-подхода для совершенствования управления ИТ-сервисами организаций. Рассмотрена взаимосвязь этапов реализации данной методологии с точки зрения системного анализа.
Сазанова Л.А.
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Other title: System and Services Acquisition Security Controls 2100-13
, 2020 [2020 update]; At head of title: DAS Policy; "Effective date: 12/22/2017."; Policy number: 2100-13; "Revision history: 12/22/2017, Original Policy; 12/20/2018, Conducted review, no changes made to the policy as a result; 06/10/2020, Updated the policy ...
Ohio. Department of Administrative Services
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Consumer handbook for vocational rehabilitation services. 2012: Jan.
, 2003 Title from PDF cover (viewed May 18, 2007).; "May 2003."; This handbook is designed to provide general information about the vocational rehabilitation program offered through the Connecticut Dept.
Connecticut. Bureau of Rehabilitation Services.
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TASK Quarterly, 2020 Currently, the European Commission puts emphasis on supporting collaboration between universities and business. There are many possible ways to create a strong relationship between both these parties.
HENRYK KRAWCZYK, PAWEŁ LUBOMSKI
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FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Telecommunications utility services
, 2004 Title from PDF caption (viewed Mar. 11, 2005).; "Effective: 12/01/2004."; Harvested from the web on 3/11/05This policy provides requirements concerning the acquisition of telecommunications utility services such as local and longdistance calling, and ...
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