Results 51 to 60 of about 2,186,662 (266)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Differentiated Development in the School in Particular Motivation
Multidisciplinary Journal of School Education, 2019 One of the main tasks of education is the appropriate motivation of students. The authors present their investigations in the field of learning motivation, which are the elements of significant research; they examine how differentiated education affects ...
Ágota Szabóné Balogh +1 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
DECISION IN ACCOUNTING USING TOOLS IT&C [PDF]
Annals of the University of Oradea: Economic Science, 2014 Taking a management decision is usually a complex endeavour with many stages. Gathering and assimilating information supposes perception processes based on attitudes which are determined by the values and fundamental beliefs of the individual.
MARES MARIUS DANIEL +3 more
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Using the Tools to Teach the Tools
Music Theory Online, 1997 The Eastman School of Music is engaged in a school-wide initiative to broaden the scope of traditional music education, and to build new audiences for art music in future generations. As part of this endeavor, students in a new technology course are learning to experience and teach music in a new way through the power of multimedia computing.
Alexander Brinkman +1 more
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
USE OF IT TOOLS IN NONCONVENTIONAL TECHNOLOGY APPLICATIONS
Nonconventional Technologies Review, 2023 For the first time, computers could be an important part of measuring systems more than 20 years ago thanks to serial communications like RS-232 and GPIB.
Dorin Vasile Deac-Suteu +3 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Why should SME adopt IT enabled CRM strategy? [PDF]
Informatică economică, 2007 Recent trends of fast adoption of CRM, whether as a philosophy, a strategy, an aid to the general marketing effort and mix, or merely as a fashion; as every body else is doing it; is driven by a clear acknowledgement and recognition that long-term ...
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