Results 71 to 80 of about 2,186,662 (266)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The SynchAADL2Maude Tool [PDF]

, 2012
SynchAADL2Maude is an Eclipse plug-in that uses Real-Time Maude to simulate and model check Synchronous AADL models. Synchronous AADL is a variant of the industrial modeling standard AADL that supports the modeling of synchronous embedded systems.
Kyungmin Bae, Peter Csaba Ölveczky, José Meseguer 0001, Abdullah Al-Nayeem   +3 more
openaire   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Modelling of a multi-seam hard coal deposit using IT tools [PDF]

E3S Web of Conferences
With the rising demand for mineral resources, efficient deposit management has become a critical challenge in modern mining. This article underscores the significance of geological modeling in coal deposit management, emphasizing the essential role that ...
Kowalczyk-Kępa Iwona, Sobczyk Eugeniusz J., Kulpa Jarosław   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

BARCRAWL and BARTAB: software tools for the design and implementation of barcoded primers for highly multiplexed DNA sequencing

BMC Bioinformatics, 2009
Background Advances in automated DNA sequencing technology have greatly increased the scale of genomic and metagenomic studies. An increasingly popular means of increasing project throughput is by multiplexing samples during the sequencing phase.
Frank Daniel N
doaj   +1 more source

7 Tool and 7 New Tools

, 2017
Dalam menentukan kualitas sesuatu diperlukan beberapa metode untuk menentukan standar. Cara yang sering digunakan dewasa ini yaitu tujuh alat termasuk untuk menentukan keputusan. Saat ini telah berkembang pula metode untuk mengambil keputusan dalam menentukan kualitas yaitu salah satu contohnya Delphi.
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Archaeological Map of Ancona: new IT tools

Groma
This paper presents the technological innovations introduced to the Archaeological Map of Ancona (Italy) in 2024, when the platform was first published online.
Eleonora Iacopini
doaj   +1 more source