Results 51 to 60 of about 847,640 (292)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Nuevas aproximaciones a la historia urbana de Italia: el Renacimiento temprano

open access: yesHispania, 1998
La interpretación de la historia de la Baja Edad Media y la temprana Edad Moderna de Italia ha estado desde el siglo pasado fuertemente influida por la dicotomía norte-sur y los modelos centro-periferia. Este artículo desmonta los argumentos del dualismo
S. R. Epstein
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Derecho y práctica legal en las comunas urbanas italianas del siglo XII: el caso de pisa

open access: yesHispania, 1997
Pisa no fue una ciudad típica en la Italia del siglo XII; grande y comercialmente próspera, con instituciones urbanas precoces, destaca, sobre todo, por su adopción del Derecho Romano con un grado de compromiso mayor que cualquier otra entidad política a
Chris Wickham
doaj   +1 more source

What is the Philology Author? [PDF]

open access: yes, 2014
Este artículo pretende definir la filología de autor y, para ello, atenderá a su génesis, donde cobran especial importancia las figuras de Contini e Isella, a sus premisas básicas, que la diferencian de la crítica genética francesa y al radical ...
Italia, Paola, Raboni, Giulia
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

PREDICTING WILLINGNESS-TO-PAY A PREMIUM FOR ORGANICALLY GROWN FRESH PRODUCE [PDF]

open access: yes
Consumers were surveyed at various grocery retail establishments in New Jersey to provide opinions on organic produce. The objective of this study was to empirically evaluate which demographic characteristics cause consumers to be more likely to pay a ...
Govindasamy, Ramu, Italia, John
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Evaluating Consumer Usage of Nutritional Labeling: The Influence of Socio-Economic Characteristics [PDF]

open access: yes
The majority of consumers report making frequent use of nutritional labeling when purchasing food products. However, certain segments appear to place a greater emphasis on food product labels than others.
Govindasamy, Ramu, Italia, John
core   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

open access: yes
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari   +9 more
wiley   +1 more source

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