Results 111 to 120 of about 25,829,571 (300)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
lordif: An R Package for Detecting Differential Item Functioning Using Iterative Hybrid Ordinal Logistic Regression/Item Response Theory and Monte Carlo Simulations [PDF]
Logistic regression provides a flexible framework for detecting various types of differential item functioning (DIF). Previous efforts extended the framework by using item response theory (IRT) based trait scores, and by employing an iterative process ...
Seung W. Choi +2 more
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Validity analysis (factor loading) of dimensions and item analysis.
, 2020 Validity analysis (factor loading) of dimensions and item analysis.
Yi-Min Hung (8407455) +2 more
core +1 more source
Educational ChallengesPurpose. In Ukrainian universities, first-year English for Specific Purposes (ESP) classes are usually formed from academic groups defined by degree programme, not by language level.
Volodymyr Kshevetskiy
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2003 This paper presents the findings of an exploratory item analysis into student performance on two PDP modules and a Scheme module assessed by CBA. The purpose is to investigate if CBA holds the potential to fulfil a diagnostic function over and above
Analysis For Profiling, Carol Collins
core
Saudi Journal for Health SciencesBackground: Artificial intelligence (AI) tools are increasingly used for preexam item analysis, but their predictive validity remains uncertain. Aims: This study aimed to compare AI-predicted item difficulty and discrimination with actual postexam ...
Ahmad S. Alamro
doaj +1 more source