Results 161 to 170 of about 25,829,571 (300)

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

ItemSight: Development of a Shiny Application for Simplified Item Analysis of Type A Multiple-Choice Questions. [PDF]

Cureus
Mondal H, Sarangi PK, Mondal S, Dhanvijay AD, Gayen RK, Mukhopadhyay A, Mishra R.   +6 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Evaluating single-best-answer questions in dental materials education: a retrospective item analysis from an online undergraduate dentistry question bank. [PDF]

BDJ Open
Vij O, Herbert A, Penning-Lambert J, Longbone T, Deb S.   +4 more
europepmc   +1 more source

Internal Consistency and Item Analysis of the Persian Version of the Child Sensory Profile 2 in Vulnerable Populations. [PDF]

Iran J Psychiatry, 2021
Mirzakhani N, Rezaee M, Alizadeh Zarei M, Mahmoudi E, Rayegani SM, Shahbazi M, Haddadiniya A.   +6 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Item analysis of the gastroesophageal reflux disease quality of life instrument QLICD-GERD based on classical test theory and item response theory. [PDF]

BMC Gastroenterol
Mu Z, Song T, Gao Y, Huang Q, Xia X, Fu T, Xu J, Sun H, Liu Y, Chen Y.   +9 more
europepmc   +1 more source

An item analysis according to the Rasch model of the German 12-item WHO Disability Assessment Schedule (WHODAS 2.0). [PDF]

Qual Life Res, 2021
Vaganian L, Bussmann S, Boecker M, Kusch M, Labouvie H, Gerlach AL, Cwik JC.   +6 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Item Analysis [PDF]

, 2011
  +4 more sources