Results 91 to 100 of about 2,443,182 (340)

The influence of diversity on the measurement of functional impairment: An international validation of the Amsterdam IADL Questionnaire in eight countries

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Introduction To understand the potential influence of diversity on the measurement of functional impairment in dementia, we aimed to investigate possible bias caused by age, gender, education, and cultural differences. Methods A total of 3571 individuals
Mark A. Dubbelman, Merike Verrijp, David Facal, Gonzalo Sánchez‐Benavides, Laura J.E. Brown, Wiesje M. vander Flier, Hanna Jokinen, Athene Lee, Iracema Leroi, Cristina Lojo‐Seoane, Vuk Milošević, José Luís Molinuevo, Arturo X. Pereiro Rozas, Craig Ritchie, Stephen Salloway, Gemma Stringer, Stelios Zygouris, Bruno Dubois, Stéphane Epelbaum, Philip Scheltens, Sietske A.M. Sikkes   +20 more
doaj   +1 more source

On Popularity Bias of Multimodal-aware Recommender Systems: a Modalities-driven Analysis [PDF]

arXiv, 2023
Multimodal-aware recommender systems (MRSs) exploit multimodal content (e.g., product images or descriptions) as items' side information to improve recommendation accuracy. While most of such methods rely on factorization models (e.g., MFBPR) as base architecture, it has been shown that MFBPR may be affected by popularity bias, meaning that it ...
arxiv  

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Text Matching Improves Sequential Recommendation by Reducing Popularity Biases [PDF]

arXiv, 2023
This paper proposes Text mAtching based SequenTial rEcommendation model (TASTE), which maps items and users in an embedding space and recommends items by matching their text representations. TASTE verbalizes items and user-item interactions using identifiers and attributes of items.
arxiv  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Bias and Linking Error in Fixed Item Parameter Calibration

AppliedMath
The two-parameter logistic (2PL) item response theory (IRT) model is frequently applied to analyze group differences for multivariate binary random variables.
Alexander Robitzsch
doaj   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

Exploring reporting quality of systematic reviews and Meta-analyses on nursing interventions in patients with Alzheimer’s disease before and after PRISMA introduction

BMC Medical Research Methodology, 2018
Background Systematic reviews (SRs) and meta-analyses (MAs) are distillation of current best available evidence, but are potentially prone to bias. The bias of SRs and MAs comes from sampling bias, selection bias and within study bias.
Xiao Sun, Xiaobin Zhou, Yan Yu, Haihua Liu   +3 more
doaj   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source