Results 71 to 80 of about 3,022,639 (245)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Risk of bias by item in the assessment instrument.
, 2015 Risk of bias by item in the assessment instrument.
Guosheng Yin (253572) +4 more
core +1 more source
, 2015 Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
Luisa Roeder (765468) +4 more
core +2 more sources
A Short Note on Aberrant Responses Bias in Item Response Theory
Frontiers in Psychology, 2019 Item response models often cannot calculate true individual response probabilities because of the existence of response disturbances (such as guessing and cheating).
Bing Jia, Xue Zhang, Zhemin Zhu
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Risk-of-bias summary: the authors’ judgments about each risk-of-bias item for the included studies.
, 2014 Risk-of-bias summary: the authors’ judgments about each risk-of-bias item for the included studies.
Jiandong Lin (138764) +4 more
core +1 more source
, 2015 Risk of bias summary: review authors' judgments about each risk of bias item for each included study.
Na Li (6550) +5 more
core +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2019 Risk of bias summary: Review authors’ judgements about each risk of bias item for each included study.
Joy C. MacDermid (4279753) +4 more
core +2 more sources