Results 71 to 80 of about 3,462,089 (291)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
BIAS Bulletin. The Newsletter of Brent Irish Advisory Service. 1987 [PDF]
, 1987 Newsletter of Brent Irish Advisory Service (BIAS), 1987.
Brent Irish Advisory Service +1 more
core +4 more sources
Statistical Bias in Maximum Likelihood Estimators of Item Parameters [PDF]
Psychometrika, 1982 Asymptotic formulas are derived for the bias in the maximum likelihood estimators of the item parameters in the logistic item response model when examinee abilities are known. Numerical results are given for a typical verbal test for college admission.
openaire +1 more source
, 2017 De wijzigingsvoorstellen voor Coördinatieverordening 883/2004 en de ex ante ...
ITEM, Montebovi, Saskia
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Brief Report: An Evaluation of Item Bias on the Functional Activities Questionnaire. [PDF]
Arch Clin Neuropsychol, 2023 González DA +3 more
europepmc +1 more source