Results 61 to 70 of about 3,462,089 (291)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Psychometric properties of the WBIS/-M in a representative prebariatric sample – evidence for an improved 10-item version

open access: yesObesity Facts
Introduction The Weight Bias Internalization Scale and the Modified Weight Bias Internalization Scale are well-established self-report questionnaires for assessing weight bias internalization, which is widespread among bariatric patients.
Simon Schraven   +9 more
doaj   +1 more source

Exploring differential item functioning in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

open access: yesBMC Musculoskeletal Disorders, 2012
Background The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a widely used patient reported outcome in osteoarthritis. An important, but frequently overlooked, aspect of validating health outcome measures is to establish if ...
Pollard Beth   +2 more
doaj   +1 more source

Item Bias in a Test of Reading Comprehension [PDF]

open access: yesApplied Psychological Measurement, 1981
The possibility that certain features of items on a reading comprehension test may lead to biased esti mates of the reading achievement of particular sub groups of students was investigated. Eight nonover lapping subgroups of students were defined by the combinations of three factors: student grade level (fifth or sixth), income level of the ...
Linn, Robert L.   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

How value-glamour investors use financial information:UK evidence of investor’s confirmation bias [PDF]

open access: yes, 2014
The paper investigates investor’s behaviour in the context of value–glamour investing and fundamental analysis, and provides a direct test of the confirmation bias by bringing together the evidence from several strands of literature into a well-defined ...
Duong, Chau   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Estimasi True Score pada Second Order Unidimensional Data: Sebuah Studi Simulasi Monte Carlo Tentang Dampak Panjang Tes, Tingkat Kesukaran dan Daya Pembeda Item

open access: yesJurnal Pengukuran Psikologi dan Pendidikan Indonesia, 2019
Tujuan penelitian ini adalah untuk mengetahui apakah terdapat perbedaan atau bias pada data unidimensional second order namun sering diperlakukan sebagai unidimensional hanya pada tingkat pertama atau first order, serta mengetahui sejauh mana pengaruh ...
Puti Febrayosi
doaj   +1 more source

The interaction between unit and item nonresponse in view of the reverse cooperation continuum [PDF]

open access: yes
The paper addresses two questions. First, is item nonresponse (INR) a precursor of panel attrition (UNR), as predicted by the theory of a latent cooperation continuum, or is the interrelation of another type?
Oliver Serfling
core  

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