Results 141 to 150 of about 2,992,674 (293)
Peabody Developmental Motor Scales-2: The Use of Rasch Analysis to Examine the Model Unidimensionality, Motor Function, and Item Difficulty. [PDF]
Valentini NC, Zanella LW.
europepmc +1 more source
Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo +11 more
wiley +1 more source
ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki +7 more
wiley +1 more source
Semisupervised Learning Method to Adjust Biased Item Difficulty Estimates Caused by Nonignorable Missingness in a Virtual Learning Environment. [PDF]
Xue K, Huggins-Manley AC, Leite W.
europepmc +1 more source
Parkinson Disease Subtype Stability and Eventual Convergence
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok +10 more
wiley +1 more source
Item Difficulty of the Tactual Performance Test Location Score
The item difficulty and discrimination index values for the Tactual Performance Test Location scores are presented. The difference between this and the previous item analysis of the Location score is that in this analysis the subjects' Location scores ...
Robin L. Dutra, Richard A. Charter
core +1 more source
Efficiency of computerized adaptive testing with a cognitively designed item bank
An item bank is key to applying computerized adaptive testing (CAT). The traditional approach to developing an item bank requires content experts to design each item individually, which is a time-consuming and costly process. The cognitive design system (
Hao Luo, Xiangdong Yang
doaj +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Setting Accommodation and Item Difficulty [PDF]
This study used multilevel measurement modeling to examine the differential difficulties of math and reading items for Grade 6 students participating in Ontario’s provincial assessment in 2005-2006, in relation to whether they received a setting ...
Lin, Pei-Ying
core
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla +8 more
wiley +1 more source

