Results 41 to 50 of about 90,928 (301)
MBI_HSS item homogeneity, discrimination, and distributional form.
MBI_HSS item homogeneity, discrimination, and distributional form.
Daniela Converso (674046) +2 more
core +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Rhythm detection for speech-music discrimination in MPEG compressed domain [PDF]
A novel approach to speech-music discrimination based on rhythm (or beat) detection is introduced. Rhythmic pulses are detected by applying a long-term autocorrelation method on band-passed signals.
Murphy, Noel +7 more
core +1 more source
We aimed to develop an item bank of computerized adaptive testing for eating disorders (CAT-ED) in Chinese university students to increase measurement precision and improve test efficiency.
Kai Liu +3 more
doaj +1 more source
This study adopted an item response theory to evaluate the Grit-S scale and its dimensions (i.e., Consistency of interest [G-CI] and Perseverance of effort [G-PE]) among university students (N = 450) using two unidimensional Graded Response (GR ...
Amal Alhadabi
doaj +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The Use of Three-Option Multiple Choice Items for Classroom Assessment
Although multiple-choice items (MCIs) are widely used for classroom assessment, designing MCIs with sufficient number of plausible distracters is very challenging for teachers.
Erkan Hasan Atalmış
doaj +3 more sources
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

