Results 71 to 80 of about 6,770,640 (284)

Potential application of item-response theory to interpretation of medical codes in electronic patient records [PDF]

, 2011
Background: electronic patient records are generally coded using extensive sets of codes but the significance of the utilisation of individual codes may be unclear. Item response theory (IRT) models are used to characterise the psychometric properties of
Van Staa, Tjeerd; id_orcid, Little, P., Delaney, B., Delaney, Brendan, Wolfe, C., van Staa, Tjeerd, Gulliford Martin C, Grieve Andy, Gulliford, M.C., Charlton, Judith, Gulliford, Martin C., Little, Paul, Martin C Gulliford, Grieve, A., van Staa, T., Yardley, L., Dregan Alex, Dregan, A., Moore, M., Taweel, Adel, Andy Grieve, Moore, Michael, Charlton, J., Dregan, Alex; id_orcid, Taweel, A., Tjeerd van Staa, Dregan, Alex, Yardley, Lucy, van Staa Tjeerd, null null, Wolfe, Charles, Rudd, A., Gulliford, Martin C, Rudd, Anthony, eCRT Research Team, Grieve, Andy, Alex Dregan   +36 more
core   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

MBI_HSS item homogeneity, discrimination, and distributional form.

, 2014
MBI_HSS item homogeneity, discrimination, and distributional form.
Daniela Converso (674046), Barbara Loera (674045), Sara Viotti (674047)   +2 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Development and validation of an end stage kidney disease awareness survey: Item difficulty and discrimination indices

, 2022
INTRODUCTION: Lack of awareness for chronic kidney disease (CKD), including end stage kidney disease (ESKD) and their management options is a major impediment to patients being able to select and use home dialysis therapies.
Segal, Emma, Shell, Popy, Ashutosh M Shukla, Shukla, Ashutosh M., Olanrewaju Olaoye, Popy Shell, Emma Segal, Colin Hinkamp, Orozco, Tatiana, Hinkamp, Colin, Tatiana Orozco, Olaoye, Olanrewaju   +11 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Psychometric Evaluation of Forensic Medicine Multiple-Choice Questions: An Item Analysis From a Nepali Medical College

Journal of Medical Education and Curricular Development
Background Multiple-choice questions (MCQs) are test items that are essential to assess the competency of medical students in forensic medicine. However, the psychometric quality of these test items in Nepali medical colleges remains largely unexplored ...
Alok Atreya, Devi Ram Acharya, Samata Nepal, Laxmi Prasad Sapkota, Ritesh G. Menezes, Bal Chandra Luitel   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Development and validation of a questionnaire to assess primary health professional's knowledge of weight management counseling of adolescents in Indonesia

PEC Innovation
Objective: This study set out to develop and validate a measure of primary health professionals' knowledge of counseling for weight management in adolescent patients in Indonesia. Methods: A literature review informed the development of an initial set of
Fransisca Handy Agung, Rini Sekartini, Nani Cahyani Sudarsono, Aryono Hendarto, Retno Asti Werdhani, Meita Dhamayanti, Sri Retno Pudjiati, Lathifah Hanum, Khairunisa Mubarokah, Astrid Setyannisa, Affan Naufal, Susan M. Sawyer   +11 more
doaj   +1 more source