Results 91 to 100 of about 13,591,879 (306)

Anchor methods for DIF detection: A comparison of the iterative forward, backward, constant and all-other anchor class [PDF]

open access: yes, 2013
In the analysis of differential item functioning (DIF) using item response theory (IRT), a common metric is necessary to compare item parameters between groups of test-takers.
Zeileis, Achim   +2 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Markov Chain Monte Carlo Estimation of Normal Ogive IRT Models in MATLAB [PDF]

open access: yes
Modeling the interaction between persons and items at the item level for binary response data, item response theory (IRT) models have been found useful in a wide variety of applications in various fields. This paper provides the requisite information and
Yanyan Sheng
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Comparative Study of Item Response Theory Models for Mixed Discrete-Continuous Responses

open access: yesJournal of Intelligence
Language proficiency assessments are pivotal in educational and professional decision-making. With the integration of AI-driven technologies, these assessments can more frequently use item types, such as dictation tasks, producing response features with ...
Cengiz Zopluoglu, J. R. Lockwood
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Joint Testlet Cognitive Diagnosis Modeling for Paired Local Item Dependence in Response Times and Response Accuracy

open access: yesFrontiers in Psychology, 2018
In joint models for item response times (RTs) and response accuracy (RA), local item dependence is composed of local RA dependence and local RT dependence. The two components are usually caused by the same common stimulus and emerge as pairs.
Peida Zhan, Manqian Liao, Yufang Bian
doaj   +1 more source

Avaliação de desempenho logístico no serviço ao cliente baseada na teoria da resposta ao item [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Produção, Florianópolis, 2011A busca por alternativas para avaliar o desempenho logístico foi o que instigou esta pesquisa.
Vey, Ivan Henrique
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Response to: On item response theory models in allostatic load scoring

open access: yesComprehensive Psychoneuroendocrinology, 2021
Shelley H. Liu   +3 more
doaj   +1 more source

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