Results 141 to 150 of about 14,062,107 (346)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Norming of the Sports Intelligence Measurement Tool in Samples of Athletes and Non-Athletes: Application of Multidimensional Item Response Theory Models [PDF]
مجله علوم روانشناختیBackground: Sports intelligence plays a critical role as the ability to process and respond effectively to environmental stimuli. Numerous studies have examined the importance of intelligence components in athletic success, yet existing tools only assess
sara Abbasi +2 more
doaj
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
, 2017 When categorical ordinal item response data are collected over multiple timepoints from a repeated measures design, an item response theory (IRT) modeling approach whose unit of analysis is an item response is suitable.
Zhen Li (1234644) +2 more
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Nested Logit Models for Multiple-Choice Item Response Data
Multiple-choice items, multiple-choice models, nested logit models, nominal response model, marginal maximum likelihood estimation, item information, distractor selection information, distractor category collapsibility,
Youngsuk Suh, Daniel Bolt
core +1 more source
Singularities of Multidimensional Item Response Models and the Rank of the Fisher Information Matrix [PDF]
Joe Suzuki
openalex +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Item mapping for customized 360-degree-feedback models [PDF]
, 1999 Plan BMany organizational consulting firms use the method of 360-Degree-Feedback to assess managers and executives for their clients. Information from this instrument outlines specific development and training needs for the clients’ organization. It also
Tetrault, Tisha A.
core