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Generalizability theory and item response theory [PDF]

, 2012
Item response theory is usually applied to items with a selected-response format, such as multiple choice items, whereas generalizability theory is usually applied to constructed-response tasks assessed by raters. However, in many situations, raters may use rating scales consisting of items with a selected-response format. This chapter presents a short
openaire   +3 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Item pre-knowledge true prevalence in clinical anatomy - application of gated item response theory model

BMC Medical Education, 2019
Background Computer and paper examinations in our days are constructed from an item pool which is regularly updated. Given the way that exams are created, one of the major concerns is the security of the items that are being used in order to ensure a ...
Milton Severo, Fernanda Silva-Pereira, Maria Amelia Ferreira, Magda Monteiro, Isabel Pereira   +4 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Item Response Theory

(1) Item Response Theory (IRT) is incorrect theory for high-stake scoring; (2) IRT has no additive structure; IRT has no decomposition theory; (3) IRT is not consistent with Total Score and General Total Score; (4) IRT is not self-consistent; IRT is not complete;
openaire   +2 more sources

An empirical comparison of Item Response Theory and Classical Test Theory [PDF]

Psihološka Obzorja, 2008
Based on nonlinear models between the measured latent variable and the item response, item response theory (IRT) enables independent estimation of item and person parameters and local estimation of measurement error.
Špela Progar, Gregor Sočan
doaj  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

ITEM ANALYSIS OF HIGH SCHOOL SPECIALIZATION MATHEMATICS EXAM QUESTIONS WITH ITEM RESPONSE THEORY APPROACH

Barekeng
Analysis of item characteristics on test instruments is carried out to determine high-quality items. This study aims to describe the parameters of specialized high school mathematics test items using the IRT approach.
Lovieanta Arriza, Heri Retnawati, Rizki Tika Ayuni   +2 more
doaj   +1 more source

Network Security Risk Assessment Based on Item Response Theory

EAI Endorsed Transactions on Security and Safety, 2015
Owing to the traditional risk assessment method has one-sidedness and is difficult to reflect the real network situation, a risk assessment method based on Item Response Theory (IRT) is put forward in network security.
Fangwei Li, Qing Huang, Jiang Zhu, Zhuxun Peng   +3 more
doaj   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source