Results 111 to 120 of about 720,756 (326)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Marginal Maximum Likelihood Estimation of Item Response Models in R [PDF]
Item response theory (IRT) models are a class of statistical models used by researchers to describe the response behaviors of individuals to a set of categorically scored items.
Matthew S. Johnson
core +1 more source
Item Response Theory Model for Understanding Item Non- Response in Ghanaian Surveys [PDF]
, 2014 This paper explores four Item Response Theory (IRT) models to determine the most appropriate forunderstanding item non-response. The selected IRT model was used to identify among five categories of surveyquestions, the most difficult to answer by ...
Amoamah, Martin Owusu +2 more
core +1 more source
Anchor methods for DIF detection: A comparison of the iterative forward, backward, constant and all-other anchor class [PDF]
, 2013 In the analysis of differential item functioning (DIF) using item response theory (IRT), a common metric is necessary to compare item parameters between groups of test-takers.
Zeileis, Achim +2 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Estimation of Item Response Models with the lmer Function from the lme4 Package in R [PDF]
In this paper we elaborate on the potential of the lmer function from the lme4 package in R for item response (IRT) modeling. In line with the package, an IRT framework is described based on generalized linear mixed modeling. The aspects of the framework
Ivailo Partchev +6 more
core +1 more source
Benchmarking by Item Response Theory (BIRTH): método de benchmarking utilizando a teoria da resposta ao item na construção de escalas de competitividade [PDF]
, 2014 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Produção, Florianópolis, 2014.Este trabalho desenvolve um novo método de benchmarking, que permite a construção de escalas de ...
Pacheco, Juliano Anderson
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Item response theory calibration results. [PDF]
, 2019 Item response theory calibration results.
Janhavi Ajit Vaingankar (2164432) +12 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source