Results 121 to 130 of about 12,812,359 (296)

Multidimensional item response theory /

, 2020
"Several decades of psychometric research have led to the development of sophisticated models for multidimensional test data, and in recent years, multidimensional item response theory (MIRT) has become a burgeoning topic in psychological and educational
Bonifay, Wesaut
core  

Avaliação de desempenho logístico no serviço ao cliente baseada na teoria da resposta ao item [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Produção, Florianópolis, 2011A busca por alternativas para avaliar o desempenho logístico foi o que instigou esta pesquisa.
Vey, Ivan Henrique
core  

Reliability of test scores in nonparametric item response theory

, 1987
Mokken scaling, nonparametric item response theory, reliability estimates, distributional properties,
SIJTSMA, K, Molenaar, Ivo W., Ivo Molenaar, Klaas Sijtsma, Ivo W. Molenaar   +4 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Funcionamento diferencial dos itens do Teste Cloze por Opção

Arquivos Brasileiros de Psicologia, 2011
This study analyzed the differential item functioning of Teste Cloze por Opção EM/U that assess collectively reading comprehension. The subjects were 489 students.
Maria Cristina Rodrigues Azevedo Joly, Nayane Martoni Piovezan   +1 more
doaj  

Item parameter estimates using item response theory for individual HRQoL domains.

, 2014
RMSEA: root mean square error of approximation.Item parameter estimates using item response theory for individual HRQoL domains.
Pranav K. Gandhi (636486), Sanjeev Y. Tuli (636488), I-Chan Huang (636491), Lindsay A. Thompson (636487), Elizabeth Shenkman (636490), Dennis A. Revicki (636489)   +5 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

A Psychometric Perspective on the Associations between Response Accuracy and Response Time Residuals

Journal of Intelligence
We provide an alternative psychometric perspective on the empirical statistical dependencies observed between response accuracy residuals (RARs) and response time residuals (RTRs) in the context of the van der Linden model.
Weicong Lyu, Daniel Bolt
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source