Results 91 to 100 of about 12,425,968 (292)

Adapting cognitive diagnosis computerized adaptive testing item selection rules to traditional item response theory.

PLoS ONE, 2020
Currently, there are two predominant approaches in adaptive testing. One, referred to as cognitive diagnosis computerized adaptive testing (CD-CAT), is based on cognitive diagnosis models, and the other, the traditional CAT, is based on item response ...
Miguel A Sorrel, Juan R Barrada, Jimmy de la Torre, Francisco José Abad   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The Estimation of Item Response Models with the lmer Function from the lme4 Package in R [PDF]

In this paper we elaborate on the potential of the lmer function from the lme4 package in R for item response (IRT) modeling. In line with the package, an IRT framework is described based on generalized linear mixed modeling. The aspects of the framework
Ivailo Partchev, Francis Tuerlinckx, Robert Zwitser, Abe Hofman, Marjan Bakker, Michel Nivard, Paul De Boeck   +6 more
core  

Forced Choice Assessment of Work Related Maladaptive Personality Traits: Preliminary Evidence from an Application of Thurstonian Item Response Modeling [PDF]

, 2016
This article describes an investigation of whether Thurstonian item response modeling is a viable method for assessment of maladaptive traits. Forced-choice responses from 420 working adults to a broad-range personality inventory assessing six ...
Cooper, Andrew J., Guenole, Nigel, Brown, Anna, Cooper, Andrew   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Benchmarking by Item Response Theory (BIRTH): método de benchmarking utilizando a teoria da resposta ao item na construção de escalas de competitividade [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Produção, Florianópolis, 2014.Este trabalho desenvolve um novo método de benchmarking, que permite a construção de escalas de ...
Pacheco, Juliano Anderson
core  

Anchor methods for DIF detection: A comparison of the iterative forward, backward, constant and all-other anchor class [PDF]

, 2013
In the analysis of differential item functioning (DIF) using item response theory (IRT), a common metric is necessary to compare item parameters between groups of test-takers.
Zeileis, Achim, Kopf, Julia, Strobl, Carolin   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Anchor selection strategies for DIF analysis: Review, assessment, and new approaches [PDF]

, 2013
Differential item functioning (DIF) indicates the violation of the invariance assumption for instance in models based on item response theory (IRT). For item-wise DIF analysis using IRT, a common metric for the item parameters of the groups that are to ...
Zeileis, Achim, Kopf, Julia, Strobl, Carolin   +2 more
core   +1 more source

Automating Simulation Research for Item Response Theory using R

International Journal of Assessment Tools in Education, 2018
A simulation study is a useful tool in examininghow validly item response theory (IRT) models can be applied in various settings.Typically, a large number of replications are required to obtain the desired precision.However, many standard software ...
Sunbok Lee, Allan S. Cohen, Youn-jeng Choi   +2 more
doaj   +1 more source