Results 121 to 130 of about 1,160,716 (327)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Integrated Item Response Theory Modeling of Multiple Patient-Reported Outcomes Assessing Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia [PDF]
, 2020 Yassine Kamal Lyauk +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
MODELING NONIGNORABLE MISSING DATA WITH ITEM RESPONSE THEORY (IRT) [PDF]
, 2010 Norman Rose +2 more
openalex +1 more source
ANALYSIS AND EVALUATION OF MULTIPLE-CHOICE TEST ITEMS AND TEST DESIGN: A STUDY ON APPLICATION OF ITEM RESPONSE THEORY [PDF]
, 2021 Nguyễn Văn Cảnh, Phạm Văn Tặc
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
ANALYTICAL DESCRIPTIVE STUDY OF STUDENTS’ CRITICAL MATHEMATIC THINKING ABILITY THROUGH GRADED RESPONSE MODELS (GRM [PDF]
, 2013 ZARA ZAHRA ANASHA. “ANALYTICAL DESCRIPTIVE STUDY OF STUDENTS’ CRITICAL MATHEMATIC THINKING ABILITY THROUGH GRADED RESPONSE MODELS (GRM)” Critical mathematic thinking ability is very important to solve daily problems.
ZARA ZAHRA ANASHA.,
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Markov Chain Monte Carlo Estimation of Normal Ogive IRT Models in MATLAB [PDF]
Modeling the interaction between persons and items at the item level for binary response data, item response theory (IRT) models have been found useful in a wide variety of applications in various fields. This paper provides the requisite information and
Yanyan Sheng
core +1 more source