Results 161 to 170 of about 720,756 (326)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Modeling of Responses and Response Times with the Package cirt [PDF]
In computerized testing, the test takers' responses as well as their response times on the items are recorded. The relationship between response times and response accuracies is complex and varies over levels of observation.
Wilm van der Linden +2 more
core +1 more source
Desenvolvimento de ambiente computacional para implementação de métodos da teoria da resposta ao item [PDF]
, 2007 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação.Este trabalho propõe o desenvolvimento de um software para utilização da Teoria da Resposta ao Item (TRI). A Teoria da
Justino, Gilvan
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FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
DAKS: An R Package for Data Analysis Methods in Knowledge Space Theory [PDF]
Knowledge space theory is part of psychometrics and provides a theoretical framework for the modeling, assessment, and training of knowledge. It utilizes the idea that some pieces of knowledge may imply others, and is based on order and set theory.
Anatol Sargin, Ali Ünlü
core +1 more source
Knowledge Space Theory and Item Response Theory [PDF]
, 2009 This note is part of a book chapter about recent developments in performance-based knowledge space theory.
Ünlü, Ali
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C-Test construct validity: Evidence from nonparametric item response theory
Language Testing in AsiaC-Test is a gap-filling test designed to measure first and second language proficiency. Over the past four decades, researchers have shown the fit of C-Test data to parametric item response theory (IRT) models, but no study so far has shown the fit of C ...
Roya Shoahosseini +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
A new method for detecting differential item functioning in the Rasch model [PDF]
Differential item functioning (DIF) can lead to an unfair advantage or disadvantage for certain subgroups in educational and psychological testing. Therefore, a variety of statistical methods has been suggested for detecting DIF in the Rasch model.
Carolin Strobl +2 more
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