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Limit points of the iterative scaling procedure [PDF]
The iterative scaling procedure (ISP) is an algorithm which computes a sequence of matrices, starting from some given matrix. The objective is to find a matrix 'proportional' to the given matrix, having given row and column sums. In many cases, for example if the initial matrix is strictly positive, the sequence is convergent.
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Fastest walk control of quadruped robots for trot gait by using torque redundancy of leg joints
A way of deriving the fastest walk pattern of quadruped robots for trot gait is developed and installed into a practical robot system. Two support legs and the body are modeled as a five-link manipulator and each swinging leg is modeled as a two link ...
Yuhei SUZUKI +2 more
doaj +1 more source
Spinning gluons from the QCD light-ray OPE
We study the transverse spin structure of the squeezed limit of the three-point energy correlator, ℰ n → 1 ℰ n → 2 ℰ n → 3 $$ \left\langle \mathrm{\mathcal{E}}\left({\overrightarrow{n}}_1\right)\mathrm{\mathcal{E}}\left({\overrightarrow{n}}_2\right ...
Hao Chen, Ian Moult, Hua Xing Zhu
doaj +1 more source
A generalization of the gauss limit for iterated means
It is shown that a recursive process, involving iteration of the means of order t1 < …
Everett, C.J., Metropolis, N.
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Towards motivic coactions at genus one from zeta generators
The motivic coaction of multiple zeta values and multiple polylogarithms encodes both structural insights on and computational methods for scattering amplitudes in a variety of quantum field theories and in string theory.
Axel Kleinschmidt +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The size of the largest fluctuations in a market model with Markovian switching [PDF]
This paper considers the size of the large fluctuations of a stochastic differential equation with Markovian switching. We concentrate on processes which obey the Law of the Iterated Logarithm, or obey upper and lower iterated logarithm growth bounds on ...
Wu, H., Mao, X., Appleby, J., Lynch, T.
core +3 more sources

