Results 101 to 110 of about 321,959 (297)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Approximate Modified Policy Iteration

open access: yes, 2012
Modified policy iteration (MPI) is a dynamic programming (DP) algorithm that contains the two celebrated policy and value iteration methods. Despite its generality, MPI has not been thoroughly studied, especially its approximation form which is used when
Gabillon, Victor   +3 more
core   +5 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Iteration-dependent evolution of the ANN model’s training performance for MPXV, evaluated using the mean squared error (MSE) metric.

open access: yes
Iteration-dependent evolution of the ANN model’s training performance for MPXV, evaluated using the mean squared error (MSE) metric.
Lulah Alnaji (18476031)
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Sparse Representation over Shared Coefficients in Multispectral Pansharpening

open access: yesTsinghua Science and Technology, 2018
The pansharpening process is for obtaining an enhanced image with both high spatial and high spectral resolutions by fusing a panchromatic (PAN) image and a low spatial resolution multispectral (MS) image.
Liuqing Chen   +2 more
doaj   +1 more source

Iteration-dependent evolution of the LSTM model’s training performance for MPXV, evaluated using the mean squared error (MSE) metric.

open access: yes
Iteration-dependent evolution of the LSTM model’s training performance for MPXV, evaluated using the mean squared error (MSE) metric.
Lulah Alnaji (18476031)
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

A Cross Information Fusion Method Based on Iteration for Frequency Estimation

open access: yes工程科学与技术, 2013
:In order to overcome the disadvantage of traditional method such as poor noise immunity,excessive loss of information and low information utilization,a cross information fusion method based on iteration was proposed to improve frequency estimation ...
苏丹, 涂亚庆, 罗健源, 李明
doaj  

Backtracking iterators [PDF]

open access: yesProceedings of the 2006 workshop on ML, 2006
Iterating over the elements of an abstract collection is usually done in ML using a fold-like higher-order function provided by the data structure. This article discusses a different paradigm of iteration based on purely functional, immutable cursors. Contrary to fold-like iterators, the iteration can be cleanly interrupted at any step.
openaire   +1 more source

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