Results 91 to 100 of about 321,959 (297)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Non-stationary approximate modified policy iteration [PDF]

open access: yes, 2015
International audienceWe consider the infinite-horizon γ-discounted optimal control problem formalized by Markov Decision Processes. Running any instance of Modified Policy Iteration—a family of algorithms that can interpolate between Value and Policy ...
Scherrer, Bruno, Lesner, Boris
core   +2 more sources

One-iteration-clipping-filtering (OICF) scheme for PAPR reduction of OFDM systems

open access: yes, 2008
A new scheme for iterative clipping and filtering (ICF) method is proposed for PAPR (peak-to-average power ratio) reduction of OFDM (orthogonal frequency division multiplexed) signals.
Fawaz Al-Qahtani (14176718)   +3 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Iterative Optimization of PV/T Microchannel Structure Based on Non-Uniform Parallel Arrangement

open access: yesEnergies
The traditional uniform parallel microchannel structure in PV/T system results in the formation of high-temperature zones in a silicon cell. This paper proposes using the iterative optimization to change the uniform arrangement of microchannel width to a
Bing Hong   +6 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Extensions of iterative congruences on free iterative algebras

open access: yesJournal of Computer and System Sciences, 1983
An iterative \(\Sigma\)-algebra A is a \(\Sigma\)-algebra with a unique solution for every fixpoint equation of the form \(x=p(x,a)\), with \(a\in A^ k\) and p an n-tuple of polynomial terms in \(\Sigma\) and \((n+k)\) variables. The \(\Sigma\)-algebra \(\bar R_{\Sigma}(Y)\) of total regular trees on \(\Sigma\) and Y is the free iterative algebra ...
openaire   +2 more sources

Iteration-dependent evolution of the GRU model’s training performance for MPXV, evaluated using the mean squared error (MSE) metric.

open access: yes
Iteration-dependent evolution of the GRU model’s training performance for MPXV, evaluated using the mean squared error (MSE) metric.
Lulah Alnaji (18476031)
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Iteration by iteration comparison between ASM and Simplex method for example 1.

open access: yes, 2015
Iteration by iteration comparison between ASM and Simplex method for example 1.
Nasir Touheed (701672)   +2 more
core   +1 more source

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