Results 81 to 90 of about 183,993 (269)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Structural and thermodynamic analysis of the thermal technology scheme of pulp and paper production
Известия высших учебных заведений: Проблемы энергетикиRelevance. The complexity of the structure of enterprises in the pulp and paper industry is determined by the large number of elements in the thermal technology schemes of production, reverse flows, connections with the environment in the form of ...
L. V. Plotnikova, M. V. Kalinila
doaj +1 more source
Proceedings of the 9th ACM Conference on Creativity & Cognition, 2013 Iterative Intersectioning is a body of art works that comes out of the collaboration between author and electronic artist Jen Seevinck and a community of print artists, most particularly Elizabeth Saunders (EJ) and Robert Oakman. The work shown here is concerned with the creative process of collaboration, specifically as this informs visual forms. This
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Approximate Common Solutions for a Family of Inverse Strongly Monotone Mappings
AxiomsIn 2003 W. Takahashi and M. Toyoda showed the weak convergence of an iteration process of finding the solution of a variational inequality problem for an inverse strongly monotone mapping.
Alexander J. Zaslavski
doaj +1 more source
LINGUISTIC DEVICES OF DEVELOPING TEXT FORMAL INTEGRITY
Novìtnâ Osvìta, 2015 The article provides the profound insight into the principles and means of achieving the formal text integrity. The fundamental directions of the text study have been suggested.
H. O. Matkovska
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Curve shortening by short rulers
ESAIM: Proceedings and Surveys, 2014 The aim is to construct a straight line between the two endpoints of a rectifiable curve using only a ruler, which is too short to connect them directly.
Stadler Peter
doaj +1 more source