Results 71 to 80 of about 182,295 (268)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Iterative intersections [PDF]

open access: yesProceedings of the 9th ACM Conference on Creativity & Cognition, 2013
Iterative Intersectioning is a body of art works that comes out of the collaboration between author and electronic artist Jen Seevinck and a community of print artists, most particularly Elizabeth Saunders (EJ) and Robert Oakman. The work shown here is concerned with the creative process of collaboration, specifically as this informs visual forms. This
openaire   +1 more source

Approximate Common Solutions for a Family of Inverse Strongly Monotone Mappings

open access: yesAxioms
In 2003 W. Takahashi and M. Toyoda showed the weak convergence of an iteration process of finding the solution of a variational inequality problem for an inverse strongly monotone mapping.
Alexander J. Zaslavski
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

LINGUISTIC DEVICES OF DEVELOPING TEXT FORMAL INTEGRITY

open access: yesNovìtnâ Osvìta, 2015
The article provides the profound insight into the principles and means of achieving the formal text integrity. The fundamental directions of the text study have been suggested.
H. O. Matkovska
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Curve shortening by short rulers

open access: yesESAIM: Proceedings and Surveys, 2014
The aim is to construct a straight line between the two endpoints of a rectifiable curve using only a ruler, which is too short to connect them directly.
Stadler Peter
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Load Flow Analysis in Power System Network Incorporating STATCOM: A Comparison of the Direct and Indirect Algorithm of the Newton-Raphson Method

open access: yesAdvances in Electrical and Electronic Engineering, 2019
This paper presents load flow analysis and the mathematical steady-state modeling of Static Synchronous Compensator (STATCOM) to study its effect on the power system network. More precisely, we propose a new approach method so-called direct algorithm and
Dung Vo Tien   +3 more
doaj   +1 more source

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