Results 71 to 80 of about 2,984,455 (293)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Two modified least-squares iterative algorithms for the Lyapunov matrix equations

open access: yesAdvances in Difference Equations, 2019
In this paper two modified least-squares iterative algorithms are presented for solving the Lyapunov matrix equations. The first algorithm is based on the hierarchical identification principle, which can be viewed as a surrogate of the least-squares ...
Min Sun, Yiju Wang, Jing Liu
doaj   +1 more source

Experimental validation of the factorization method to microwave imaging

open access: yesResults in Physics, 2020
The factorization method (FM) is a recently investigated non-iterative technique in various inverse scattering problems for the imaging (or identification) of unknown targets.
Won-Kwang Park
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Gradient-Based Iterative Identification for Wiener Nonlinear Dynamic Systems with Moving Average Noises

open access: yesAlgorithms, 2015
This paper focuses on the parameter identification problem for Wiener nonlinear dynamic systems with moving average noises. In order to improve the convergence rate, the gradient-based iterative algorithm is presented by replacing the unmeasurable ...
Lincheng Zhou   +3 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Application of a Dynamic Step Size Iterative Method for Parameter Inversion in the Unified Hardening Models

open access: yesApplied Sciences
The unified hardening model for clays and sands (CSUH) can adequately represent the stress–strain characteristics of various soil types. However, being an incremental elastoplastic constitutive model, the CSUH model requires extensive iterative ...
Binglong Zhu   +5 more
doaj   +1 more source

Neural Membrane Mutual Coupling Characterisation Using Entropy-Based Iterative Learning Identification

open access: yesIEEE Access, 2020
This paper investigates the interaction phenomena of the coupled axons while the mutual coupling factor is presented as a pairwise description. Based on the Hodgkin-Huxley model and the coupling factor matrix, the membrane potentials of the coupled ...
Xiafei Tang   +3 more
doaj   +1 more source

Iterative Snapping of Odometry Trajectories for Path Identification [PDF]

open access: yes, 2014
An increasing number of mobile devices are capable of automatically sensing and recording rich information about the surrounding environment. Spatial locations of such data can help to better learn about the environment. In this work, we address the problem of identifying the locations visited by a mobile device as it moves within an indoor environment.
Richard Wang   +2 more
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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