Results 51 to 60 of about 2,984,455 (293)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2019 An interactive installation of Iterative Music (a process developed by Dr Steve Gisby) in which audience members were able to upload their own sounds over a local ...
Herbert, D., Gisby, S.
core +2 more sources
Iterative Solutions of a Set of Matrix Equations by Using the Hierarchical Identification Principle
Abstract and Applied Analysis, 2014 This paper is concerned with iterative solution to a class of the real coupled matrix equations. By using the hierarchical identification principle, a gradient-based iterative algorithm is constructed to solve the real coupled matrix equations A1XB1 ...
Huamin Zhang
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Iterative integral parameter identification of a respiratory mechanics model
BioMedical Engineering OnLine, 2012 Background Patient-specific respiratory mechanics models can support the evaluation of optimal lung protective ventilator settings during ventilation therapy.
Schranz Christoph +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An iterative method for parameter identification and shape reconstruction
, 2010 An iterative strategy for the reconstruction of objects buried in a medium and the identification of their material parameters is analysed. The algorithm alternates guesses of the domains using topological derivatives with corrections of the parameters ...
Rapún Banzo, María Luisa +1 more
core +1 more source
Functional Electrical Stimulation mediated by Iterative Learning Control and 3D robotics reduces motor impairment in chronic stroke [PDF]
, 2012 Background: Novel stroke rehabilitation techniques that employ electrical stimulation (ES) and robotic technologies are effective in reducing upper limb impairments.
Cai, Z +6 more
core +2 more sources
An Extended Iterative Identification Method for the GISSMO Model
Metals, 2019 This study examines an extended method to obtain the parameters in the Generalized Incremental Stress State Dependent Damage (GISSMO) model. This method is based on an iterative Finite Element Method (FEM) method aiming at predicting the fracture ...
Yue Xiao, Yumei Hu
doaj +1 more source