Results 61 to 70 of about 2,984,455 (293)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
SICE Journal of Control, Measurement, and System Integration, 2018 This paper presents a novel unified approach of controller design and identification for unknown input affine nonlinear systems. An issue with obtaining the best performance of optimal control is that identification errors degrade control performance ...
Yuji Ito +3 more
doaj +1 more source
METHOD OF ITERATIVE IDENTIFICATION OF MULTIVARIABLE SYSTEMS OVER INEXAСT DATA. Part ІІ. ALGORITHMS
Міжнародний науково-технічний журнал "Проблеми керування та інформатики", 2007 The algorithms are developed to form one of the possible iterative schemes for multivariable linear dynamic system identification over inexact data. For realization of this scheme it is set what kind of identification experiments should be chosen and ...
V.F. Gubarev, P.А. Tigunov
doaj +1 more source
Iterative time reversal based flaw identification
Computers & Mathematics with Applications, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Robert Seidl, Ernst Rank
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Frequency domain iterative feedforward/feedback tuning for MIMO ANVC
, 2007 A new iterative feedback/feed-forward tuning (IFFT) method is presented for multiple-input multiple-output (MIMO) control systems that relies on efficient computation of the negative gradient of the controller cost function in the frequency domain.
Veres, S.M., Luo, J.
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Two-Stage Code Acquisition Employing Search Space Reduction and Iterative Detection in the DS-UWB Downlink [PDF]
, 2008 —In this paper we propose and investigate an iterative code acquisition scheme assisted by both search space reduction and iterative Massage Passing (MP), which was designed for the Direct Sequence-Ultra WideBand (DS-UWB) DownLink (DL).
Won, S, Hanzo, L
core +2 more sources
Neurology and Therapy, 2023 Background Early identification of individuals with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) is a clinical and research imperative. Use of diagnostic codes for MCI and AD identification has limitations.
Byron J. Aguilar +12 more
doaj +1 more source