Results 81 to 90 of about 47,269,723 (340)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Iterative methods for option pricing in Merton's Jump diffusion model [PDF]
, 2022 openThe main purpose of this thesis is to study numerical schemes for the solution of the PDE associated with the Merton jump-diffusion model. The implementation of these schemes will be achieved through the finite differences method, and in particular ...
BALDINA, ANDREA
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
AIR Tools II: algebraic iterative reconstruction methods, improved implementation
Numerical Algorithms, 2017 We present a MATLAB software package with efficient, robust, and flexible implementations of algebraic iterative reconstruction (AIR) methods for computing regularized solutions to discretizations of inverse problems.
P. Hansen, J. S. Jørgensen
semanticscholar +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Iterative operator-splitting methods for linear problems
, 2007 The operator-splitting methods are based on splitting of the complex problem into a sequence of simpler tasks. A useful method is the iterative splitting method which ensures a consistent approximation in each step.
Farago, Istvan, Geiser, Jürgen
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Reliable iterative methods for 1D Swift–Hohenberg equation
Arab Journal of Basic and Applied Sciences, 2020 In this paper, the nonlinear problem of the 1 D Swift-Hohenberg equation (S-HE) has been solved by using five reliable iterative methods. The first one is the Daftardar-Jafari method namely (DJM), the second method is the Temimi-Ansari method namely (TAM)
Majeed A. AL-Jawary, Othman Mahdi Salih
doaj +1 more source
Energy contraction and optimal convergence of adaptive iterative linearized finite element methods
, 2021 We revisit a unified methodology for the iterative solution of nonlinear equations in Hilbert spaces. Our key observation is that the general approach from [P. Heid and T. P.
Wihler, Thomas P. +9 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source