A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni +7 more
wiley +1 more source
Quantum linear solvers for scientific computing: a comparison of VQLS, HHL and quantum annealing on time-fractional diffusion problems. [PDF]
Shayegan AHS.
europepmc +1 more source
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega +4 more
wiley +1 more source
Development and implementation of a unified curriculum in math, statistics, computing, and informatics with financial considerations for medical physics graduate programs. [PDF]
Chang J, Vaccarelli MJ.
europepmc +1 more source
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen +7 more
wiley +1 more source
Numerical and Experimental Investigation of High-Pressure Hydrogen Jet Dispersion from Leakage at 70 MPa. [PDF]
Zhang Z +7 more
europepmc +1 more source
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha +9 more
wiley +1 more source
Hybrid expansion methods for fractional non-linear mathematical systems with Erdelyi-Kober derivative operators in theory of tsunami wave modeling. [PDF]
Damag FH +5 more
europepmc +1 more source
Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno +16 more
wiley +1 more source
Qualitative analysis and numerical simulation of ABC fractional impulsive differential systems with implicit nonlinear terms and integral boundary conditions. [PDF]
Sharif AA, Hamood M, Ghadle KP.
europepmc +1 more source

