Results 101 to 110 of about 41,330 (277)
ABSTRACT This article contributes to our understanding of the use of counter accounting in social movements, through consideration of Bakhtinian dialogics as a theoretical framing. We explore counter and dialogic accounting in a significant socio‐political conflict in the city of Sheffield, UK. Our case covers a public–private partnership (PPP) highway
Xia Shu+3 more
wiley +1 more source
Novel scientific approaches and future research directions in understanding ITP
Diagnosis of immune thrombocytopenia (ITP) and prediction of response to therapy remain significant and constant challenges in hematology. In patients who present with ITP, the platelet count is frequently used as a surrogate marker for disease severity,
Sarah M. Hicks+4 more
doaj +1 more source
Current Practice Regarding Bleeding Disorders of Unknown Cause in the Netherlands: A National Survey
ABSTRACT Introduction About 40%–70% of persons with a clinically relevant bleeding tendency who are referred to haemostasis experts are classified as having a ‘bleeding disorder of unknown cause’ (BDUC) as no biological entity can be found after extensive laboratory testing.
Caroline M. A. Mussert+15 more
wiley +1 more source
No biological predictors for the increased risk of thrombosis in patients with immune thrombocytopenia (ITP) have been identified. The aim of the study was to investigate platelet and neutrophil activation as well neutrophil extracellular trap (NET ...
Maria L Lozano+10 more
doaj +1 more source
This study aimed to compare the efficacy and safety of rituximab (RTX) plus recombinant human thrombopoietin (rhTPO) with RTX alone in patients with immune thrombocytopenia (ITP) who had failed to respond to corticosteroids or relapsed.
Hai Zhou+21 more
semanticscholar +1 more source
Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley +1 more source
Panels in Therapy. X. Treatment of Acute ITP [PDF]
C. Lockard Conley+3 more
openalex +1 more source
Mechanism of autoantibody production in ITP.
ITPは血小板に対する自己抗体により血小板破壊が亢進し,血小板減少症をきたす自己免疫疾患である.最近の研究成果により,抗血小板自己抗体の産生には血小板膜糖蛋白を認識する自己反応性CD4+T細胞が中心的な役割を果たしていることが明らかにされた.また,血小板膜糖蛋白反応性CD4+T細胞の出現機構や活性化のメカニズムも明らかにされつつある.これらの成績に基づき,抗血小板抗体産生にかかわる免疫機構を人為的に制御することによるITPの新たな治療法の開発も試みられている.
M Kuwana, Y Ikeda
openaire +4 more sources
ABSTRACT Introduction Light transmission platelet aggregometry (LTA) is useful to diagnose platelet function disorders (PFD). We evaluated the precision and reproducibility of LTA with low platelet count platelet‐rich plasma (LPRP). Methods LPRP maximal aggregation (MA) precision for informative agonists and LTA reproducibility were assessed using ...
Catherine P. M. Hayward+3 more
wiley +1 more source
The determination of phenolic compounds and antioxidant activity of grape pomace (Vitis vinifera) of two varieties: Quebranta (red) and Torontel (white) using two drying methods: freeze drying and cool air-drying was evaluated, using methods to preserve ...
A. Solari-Godiño+2 more
doaj +1 more source