Results 31 to 40 of about 30,043 (228)

Numerical and Experimental Study of Flutter in a Realistic Labyrinth Seal

open access: yesInternational Journal of Turbomachinery, Propulsion and Power
Labyrinth seals are commonly used in turbomachinery in order to control leakage flows. Flutter is one of the most dangerous potential issues for them, leading to High Cycle Fatigue (HCF) life considerations or even mechanical failure.
Oscar Bermejo   +5 more
doaj   +1 more source

Use of rituximab for treatment of HIV-infected patients with hematological disorders

open access: yesКлиническая онкогематология, 2013
Rituximab (MabThera) is one of the most powerful drug with selective action on B-cells. The drug suppresses the polyclonal antibody response to own antigens in autoimmune diseases. For lymphatic tumors it selectively acts on tumors of B-cells.
A. V. Pivnik
doaj   +1 more source

Pediatric ITP: is it different from adult ITP? [PDF]

open access: yesHematology, 2018
AbstractImmune thrombocytopenia (ITP) has historically been thought to occur in 2 distinct forms: childhood ITP and adult ITP. This division is based largely on the presumption that childhood ITP is often benign and self-limited, whereas ITP in adults tends to be more chronic and difficult to treat.
Jenny M, Despotovic, Amanda B, Grimes
openaire   +2 more sources

Pathogenesis-oriented approaches for the management of corticosteroid-resistant or relapsedprimary immune thrombocytopenia

open access: yesOpen Medicine, 2016
Primary immune thrombocytopenia (ITP) is a complex autoimmune disorder in which the patient’s immune system reacts with platelet autoantigens resulting in immune-mediated platelet destruction and/or suppression of platelet production. Corticosteroids can
Liu Xin-guang, Hou Ming
doaj   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Low‐Strain Flexible Ink‐Based Sensors Enable Hyperelastic Inflation Perception Via Geometric Patterning for Balloon‐Type Robots

open access: yesAdvanced Robotics Research, EarlyView.
Integrating proprioceptive capabilities in balloon‐type robots enhances safe human–machine interactions. Traditional pressure estimates are inadequate due to nonlinear relationships. Instead, embedding stretchable sensors effectively measures deformation. This design optimizes sensor geometry to minimize damage risks.
Wenchao Yue   +6 more
wiley   +1 more source

Endothelial alterations in a canine model of immune thrombocytopenia

open access: yesPlatelets, 2019
Bleeding heterogeneity amongst patients with immune thrombocytopenia (ITP) is poorly understood. Platelets play a role in maintaining endothelial integrity, and variable thrombocytopenia-induced endothelial changes may influence bleeding severity ...
Dana N. LeVine   +14 more
doaj   +1 more source

PENGEMBANGAN KLINIK LITERASI BERBASIS PERMAINAN BAHASA DALAM KEGIATAN LITERASI DASAR PADA MASA PANDEMI COVID-19

open access: yesPaedagoria, 2021
Abstrak: Tujuan penelitian ini untuk (1) mendeskripsikan konsep pengembangan klinik literasi berbasis permainan bahasa; (2) mendeskripsikan efektivitas pengembangan klinik literasi berbasis permainan bahasa dalam kegiatan literasi dasar pada masa pandemi
I Nengah Sueca, Ida Ayu Dewi
doaj   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

open access: yesAdvanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou   +14 more
wiley   +1 more source

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

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