Results 61 to 70 of about 41,330 (277)

Adiponectin Assists Thrombopoietic Agents in ITP Treatment by Enhancing Myosin‐9/Rab6A‐Mediated Trafficking of c‐Mpl in MKs

open access: yesAdvanced Science, EarlyView.
This study revealed that adiponectin facilitates the therapeutic efficiency of thrombopoietic agents by stimulating the membrane trafficking of c‐Mpl in MKs, which provides a point for ITP therapy. Moreover, a novel c‐Mpl trafficking mechanism based on the Myosin‐9/Rab6A complex is constructed. These findings provide new insights into the applicability
Xin Zhao   +8 more
wiley   +1 more source

Idiopathic thrombocytopenic purpura (ITP) – new era for an old disease

open access: yesRomanian Journal of Internal Medicine, 2019
Immune thrombocytopenia is an autoimmune hematological disorder characterized by severely decreased platelet count of peripheral cause: platelet destruction via antiplatelet antibodies which may also affect marrow megakaryocytes.
Onisâi Minodora   +4 more
doaj   +1 more source

Proton Acceleration with Relativistic Electromagnetic Shock

open access: yesAdvanced Science, EarlyView.
New Ion Acceleration Mechanism! A novel cosmic‐ray proton acceleration mechanism is proposed, where relativistic electromagnetic shocks accelerate protons transversely. Hamiltonian analysis yields a scaling law linking the proton energy to the minimum longitudinal thickness of the shock.
Ting Xiao   +5 more
wiley   +1 more source

Automatised matching between two scalar sectors at the one-loop level

open access: yesEuropean Physical Journal C: Particles and Fields, 2019
Nowadays, one needs to consider seriously the possibility that a large separation between the scale of new physics and the electroweak scale exists.
M. Gabelmann   +2 more
doaj   +1 more source

The incidence and clinical burden of immune thrombocytopenia in pediatric patients in the United States

open access: yesPlatelets, 2020
Immune thrombocytopenia (ITP) is the most common bleeding disorder diagnosed in children. Characterized by low platelet counts, it leads to reduced clotting abilities and an increased tendency to bleed.
Jaime Shaw   +3 more
doaj   +1 more source

ITP in the 21st Century

open access: yesHematology, 2006
Abstract Immune (or idiopathic) thrombocytopenic purpura (ITP) is commonly encountered by the practicing hematologist. Clinical management decisions have traditionally been guided by individual training and past experience. Input from the literature has been more from observational reports of case series than from scientific results of ...
openaire   +3 more sources

The thirsty fly: Ion transport peptide (ITP) is a novel endocrine regulator of water homeostasis in Drosophila

open access: yesPLoS Genetics, 2018
Animals need to continuously adjust their water metabolism to the internal and external conditions. Homeostasis of body fluids thus requires tight regulation of water intake and excretion, and a balance between ingestion of water and solid food. Here, we
M. Gáliková, H. Dircksen, D. Nässel
semanticscholar   +1 more source

Mixed Autoimmune Hemolytic Anemia: A Systematic Review of Epidemiology, Clinical Characteristics, Therapies, and Outcomes

open access: yesAmerican Journal of Hematology, EarlyView.
Mixed autoimmune hemolytic anemia (AIHA) is a rare condition characterized by the presence of both warm and cold autoantibodies, often leading to severe, treatment‐resistant hemolysis. In this systematic review of 81 patients across 35 studies, the median age was 45 years with a notable female predominance.
Jeremy W. Jacobs   +12 more
wiley   +1 more source

Addressing the Drivers and Concerns Towards Agri‐Food Strategy: Prioritizing Environmental Management Business Models

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Sustainability in the agri‐food sector has been increasingly important with regard to the environment, health, and employment of local farmers. The purpose of this research is to analyze the impact of drivers and barriers on consumer behavior toward sustainable agri‐food products in India under the Behavioral Reasoning Theory (BRT). This study
Andrea Appolloni, Debarun Chakraborty
wiley   +1 more source

Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry.

open access: yesBlood Advances, 2017
Nonspecific diagnostic criteria and uncertain estimates of severe bleeding events are fundamental gaps in knowledge of primary immune thrombocytopenia (ITP). To address these issues, we created the McMaster ITP Registry.
D. Arnold   +6 more
semanticscholar   +1 more source

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