Results 91 to 100 of about 47,734 (283)

Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy

Frontiers in Pharmacology
BackgroundItraconazole, a widely used antifungal medication, has shown potential in inhibiting tumor growth and reducing angiogenesis. However, its role in melanoma tumor growth remains insufficiently explored.
Shunqiao Jin, Shunqiao Jin, Xiaojiao Liu, Xiaojiao Liu, Lingqin Cai, Lingqin Cai, Jiayu Yan, Ling Li, Hongjun Dong, Yuxue Gao, Xicong Zhu, Cong Zhang, Xuezhu Xu   +12 more
doaj   +1 more source

Desenvolvimento e validação de metodologia analítica para determinação de itraconazol em produtos farmacêuticos por CLAE Development and validation of the methodology for evaluation of itraconazole in pharmaceutical products by HPLC

Química Nova, 2007
Itraconazole is a synthetic antifungal drug administered orally with a broad spectrum of activity against mycotic infections. The present work consists of the development and validation of analytical methodology for evaluation of itraconazole in ...
Edith Cristina Laignier Cazedey, Roberta de Cássia Pimentel Azevedo, Érika de Fátima Silva, Magali Benjamim de Araújo   +3 more
doaj   +1 more source

Disseminated Cutaneous Blastomycosis

JEADV Clinical Practice, EarlyView.
Lorena Alexandra Mija, Elio Kechichian, Carolina Lucena Fernandes   +2 more
wiley   +1 more source

Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions

Allergy, EarlyView.
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller, Celeste M. Boesjes, Roselie A. Achten, Lisa A. Beck, Alan D. Irvine, Christian Vestergaard, Marlies de Graaf, Femke van Wijk, Daphne S. Bakker, Stephan Weidinger   +9 more
wiley   +1 more source

Formulation and Characterization of Itraconazole as Nanosuspension Dosage Form for Enhancement of Solubility

Iraqi Journal of Pharmaceutical Sciences, 2019
Itraconazole is a triazole antifungal given orally for the treatment of oropharyngeal and vulvovaginal candidiasis, for systemic infections including aspergillosis, candidiasis,  and for the prophylaxis of fungal infections in immunocompromised patients.
Asmaa M. Rashid, Shaimaa N. Abdal-Hammid
doaj   +1 more source

The Crease Scale Sign as a Diagnostic Aid in Tinea Manuum

JEADV Clinical Practice, EarlyView.
Sunil Jaiswal, Shraddha Uprety, Pratichya Thapa, Prakriti Lamichhane   +3 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

A meta-analysis comparing efficacy of continuous terbinafine with intermittent itraconazole for toenail onychomycosis

Indian Journal of Dermatology, 2010
Background: Toenail onychomycosis is a challenge for clinicians to treat. While both Itraconazole and terbinafine have proven to be effective against onychomycosis, very little is known about their comparative efficacy in achieving mycological and ...
Trivedi N, Shah P
doaj  

Comparative Hepatotoxicity of Fluconazole, Ketoconazole, Itraconazole, Terbinafine, and Griseofulvin in Rats

Journal of Toxicology, 2017
Oral ketoconazole was recently the subject of regulatory safety warnings because of its association with increased risk of inducing hepatic injury. However, the relative hepatotoxicity of antifungal agents has not been clearly established.
S. Khoza, Ishmael Moyo, Denver Ncube
semanticscholar   +1 more source

Heart failure induced by itraconazole

Indian Journal of Pharmacology, 2013
Itraconazole is a broad-spectrum antifungal agent. It rarely leads to adverse the cardiovascular effects, especially heart failure. We present here a case of a 60-year-old female patient with itraconazole induced heart failure.
Hizir Okuyan, Cihan Altin
openaire   +3 more sources