Results 71 to 80 of about 26,822 (186)

Exploring the therapeutic mechanism of itraconazole combined with ritonavir on Candida albicans infection through network pharmacology and molecular docking

Frontiers in Pharmacology
BackgroundAutophagy induced by itraconazole and ritonavir was found involved in the pathogenesis of C. albicans. This study was designed to explore the possible molecular mechanism of itraconazole and ritonavir in the treatment of Candida albicans ...
Yiyang Feng, Wenli Feng, Jing Yang, Yan Ma   +3 more
doaj   +1 more source

Formulation and Characterization of Itraconazole as Nanosuspension Dosage Form for Enhancement of Solubility

Iraqi Journal of Pharmaceutical Sciences, 2019
Itraconazole is a triazole antifungal given orally for the treatment of oropharyngeal and vulvovaginal candidiasis, for systemic infections including aspergillosis, candidiasis,  and for the prophylaxis of fungal infections in immunocompromised patients.
Asmaa M. Rashid, Shaimaa N. Abdal-Hammid
doaj   +1 more source

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

Veterinary Dermatology, EarlyView.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro, Emma R. Bollig, Jennifer L. Granick   +2 more
wiley   +1 more source

Clinical and Immunological Responses to Dermatophagoides farinae Allergen Immunotherapy in Dogs With Atopic Dermatitis

Veterinary Dermatology, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) in dogs is a prevalent allergic disorder associated with environmental allergens, including the house dust mite Dermatophagoides farinae (Df). Hypothesis/Objectives To describe clinical and immunological changes over time in dogs with canine (c)AD sensitised to Df undergoing Df allergen‐specific immunotherapy (
Jakaphan Wannawong, Maturawan Tunhikorn, Pannathee Prangtaworn, Nawannaporn Saelim, Thapani Srisai, Nitaya Indrawattana, Sivapong Sungpradit, Anchalee Tungtrongchitr, Witthawat Wiriyarat   +8 more
wiley   +1 more source

Chronic cavitary pulmonary histoplasmosis treated with isavuconazole after a hypersensitivity reaction to itraconazole

Medical Mycology Case Reports
Chronic cavitary pulmonary histoplasmosis requires prolonged treatment with itraconazole. However, hypersensitivity reactions to itraconazole, though rare, pose a challenge due to limited data on the efficacy and cross-reactivity of the newer azoles.
Miguel E. Cervera-Hernandez, Sunit P. Jariwala   +1 more
doaj   +1 more source

An Unusual Case of Nannizzia praecox – Infection with new observations on the pathogen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina Antonia Langen, Dana Krüger, Karen Voss, Jochen Brasch   +3 more
wiley   +1 more source

Cutaneous Alternariosis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Kaan Yilmaz, Viola Pflüger, Cyrill Géraud   +2 more
wiley   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2682-2692, August 2026.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

An Open‐Label, 2‐Period, Fixed Sequence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of STS101 (Dihydroergotamine Nasal Powder), with and without Concomitant Itraconazole in Healthy Adult Subjects

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Dihydroergotamine (DHE) prescribing information contains a boxed warning regarding the possibility of serious and/or life‐threatening peripheral ischemia with co‐administration of strong cytochrome P450 3A4 (CYP3A4) inhibitors. The effects of the strong CYP3A4 inhibitor itraconazole on the pharmacokinetics and safety of nasally administered ...
Detlef Albrecht, Elizabeth Hussey, Richard B. Lipton   +2 more
wiley   +1 more source

From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez, Marcella Vieira Ambrosio, Marcela Eduarda Olegario Fernandes, Ewerton Garcia de Oliveira Mima   +3 more
wiley   +1 more source