Results 91 to 100 of about 48,966 (221)

Phylogenetic and Structural Analysis of Miconazole Susceptibility in Malassezia pachydermatis Isolates From Dogs With Otitis Externa

Veterinary Dermatology, EarlyView.
ABSTRACT Background An increased number of dogs with unresolved yeast otitis externa (OE) after miconazole treatment was observed at a tertiary practice. Hypothesis/Objectives To evaluate miconazole susceptibility in Malassezia pachydermatis isolates from canine OE.
Cole M. Belcher, Clarissa P. Souza, Elyas McGuire, Chien‐Che Hung, Joel D. A. Tyndall, Lois L. Hoyer   +5 more
wiley   +1 more source

Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy

Frontiers in Pharmacology
BackgroundItraconazole, a widely used antifungal medication, has shown potential in inhibiting tumor growth and reducing angiogenesis. However, its role in melanoma tumor growth remains insufficiently explored.
Shunqiao Jin, Shunqiao Jin, Xiaojiao Liu, Xiaojiao Liu, Lingqin Cai, Lingqin Cai, Jiayu Yan, Ling Li, Hongjun Dong, Yuxue Gao, Xicong Zhu, Cong Zhang, Xuezhu Xu   +12 more
doaj   +1 more source

Formulation and Characterization of Itraconazole as Nanosuspension Dosage Form for Enhancement of Solubility

Iraqi Journal of Pharmaceutical Sciences, 2019
Itraconazole is a triazole antifungal given orally for the treatment of oropharyngeal and vulvovaginal candidiasis, for systemic infections including aspergillosis, candidiasis,  and for the prophylaxis of fungal infections in immunocompromised patients.
Asmaa M. Rashid, Shaimaa N. Abdal-Hammid
doaj   +1 more source

Disseminated Histoplasmosis: An Unusual Finding at ROSE

Diagnostic Cytopathology, Volume 54, Issue 6, Page E146-E148, June 2026.
ABSTRACT We describe an unusual case in which disseminated histoplasmosis was suspected at the time of of rapid on‐site assessment (ROSE) performed during endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA). The patient was a renal transplant recipient with fever, mild anemia, bilateral lung infiltrates and mediastinal ...
Erika E. Doxtader, Jona Banzon, Sanjay Mukhopadhyay   +2 more
wiley   +1 more source

Exploring the therapeutic mechanism of itraconazole combined with ritonavir on Candida albicans infection through network pharmacology and molecular docking

Frontiers in Pharmacology
BackgroundAutophagy induced by itraconazole and ritonavir was found involved in the pathogenesis of C. albicans. This study was designed to explore the possible molecular mechanism of itraconazole and ritonavir in the treatment of Candida albicans ...
Yiyang Feng, Wenli Feng, Jing Yang, Yan Ma   +3 more
doaj   +1 more source

Toxicity of Antifungal Drugs Itraconazole and Fluconazole in Rats [PDF]

, 2004
Itraconazole and Fluconazole are the newer antifungal drugs that have been used for several years. Both these drugs have a broad-spectrum antifungal activity and currently are used to treat infections caused by Candida albicans, Aspergillus spp ...
Abdul Rahman, Nor Shahida
core  

Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples [PDF]

, 2015
Respiratory tract infections are among the most common infections in men. We reviewed literature to document their pharmacological treatments, and the extent to which therapeutic drug monitoring (TDM) is needed during treatment.
Akkerman, Onno W, Alffenaar, Jan-Willem C, Bolhuis, Mathieu S, Hofman, Susan, Koster, Remco A, Stove, Christophe, van Assen, Sander   +6 more
core   +2 more sources

Dupilumab‐Associated Palmar Erythema Successfully Treated With Fluconazole

Australasian Journal of Dermatology, EarlyView.
Katina J. Selvaraj, Geoffrey Lee
wiley   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Effect of solvent evaporation on the liquid-crystalline order of itraconazole

Scientific Reports
Solvent evaporation is widely used for the formation of amorphous active pharmaceutical ingredients. This study investigates the effect of solvent evaporation on the structure of itraconazole – an antifungal drug and a model thermotropic liquid crystal ...
Taoufik Lamrani, Luiza Orszulak, Magdalena Tarnacka, Barbara Hachula, Klaudia Nowakowska, Kamil Kaminski, Karolina Jurkiewicz   +6 more
doaj   +1 more source