Results 91 to 100 of about 56,596 (269)

Use of Pinus sylvestris L. (Pinaceae), Origanum vulgare L. (Lamiaceae), and Thymus vulgaris L. (Lamiaceae) essential oils and their main components to enhance itraconazole activity against azole susceptible/not-susceptible Cryptococcus neoformans strains

BMC Complementary and Alternative Medicine, 2018
BackgroundCryptococcal infections, besides being a problem for immunocompromised patients, are occasionally being a problem for immunocompetent patients.
D. Scalas, N. Mandras, J. Roana, Roberta Tardugno, A. Cuffini, V. Ghisetti, S. Benvenuti, V. Tullio   +7 more
semanticscholar   +1 more source

Consensus‐based Guideline on tinea capitis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The consensus‐based guideline developed under the auspices of the German Dermatological Society (DDG) is intended to provide physicians with a structured framework for clinical decision‐making in the management of patients with tinea capitis and to contribute to improved diagnostic accuracy, treatment adherence, and prevention. Tinea capitis is
Peter Mayser, Dietrich Abeck, Philipp P. Bosshard, Jochen Brasch, Georg Daeschlein, Isaak Effendy, Yvonne Gräser, Peter Höger, Julia Huynh, Maria Kinberger, Annette Kolb‐Mäurer, Katharina Antonia Langen, Bartosz Malisiewicz, Alexander Nast, Hagen Ott, Christin Pelzer, Dieter Reinel, Martin Schaller, Silke Uhrlaß, Pietro Nenoff   +19 more
wiley   +1 more source

An Unusual Case Report of Iatrogenic Metrorrhagia and Hematochezia Following Itraconazole

Clinical Dermatology Review
Itraconazole is an effective triazole antimycotic drug that has a desirable pharmacokinetic profile to combat various fungal pathogens. It acts by inhibiting ergosterol biosynthesis in fungal cell membranes.
Yashaswi Rai
doaj   +1 more source

Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways

OncoTarget, 2017
Malignant melanoma is the deadliest form of all skin cancers. Itraconazole, a commonly used systemic antifungal drug, has been tested for its anti-tumor effects on basal cell carcinoma, prostate cancer, and non-small cell lung cancer.
Guan-Zhao Liang, Mu-Sang Liu, Qiong Wang, Yongnian Shen, H. Mei, Dong-Mei Li, Weida Liu   +6 more
semanticscholar   +1 more source

The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer

The aim of this study was to develop cholic-acid-stabilized itraconazole nanosuspensions (ITZ-Nanos) with the objective of enhancing drug dissolution and oral absorption.
Han, Jihong, Liu, Jiahuan, Yin, Li, Yang, Qiang, Zong, Lanlan, Pu, Xiaohui, Chang, Sheng   +6 more
core   +1 more source

Cardiac arrest provoked by itraconazole and amiodarone interaction: a case report

Journal of Medical Case Reports, 2011
Introduction Azoles, and specifically itraconazole, are often prescribed for the treatment of fungal diseases or empirically for persistent sepsis in patients who are neutropenic or in intensive care.
Betrosian Alex, Andrianakis Ilias, Tsimogianni Angeliki M, Douzinas Emmanouil   +3 more
doaj   +1 more source

Repurposing itraconazole for the treatment of cancer.

Oncology Letters, 2017
The repurposing of drugs is becoming increasingly attractive as it avoids the lengthy process and cost implications associated with bringing a novel drug to market. Itraconazole is a broad-spectrum anti-fungal agent. An emerging body of in vivo, in vitro
R. Pounds, S. Leonard, C. Dawson, S. Kehoe   +3 more
semanticscholar   +1 more source

Treatment of systemic fungal infections with Itraconazole preparations

, 2006
イトラコナゾールは，non-albicans Candidaを含めたカンジダ属やアスペルギルス属に対しても強い抗真菌活性を示すトリアゾール系抗真菌薬である。日本ではカプセル薬のみしか市販されていないが，hydroxypropyl-β-cyclodextrin（HP-β-CD）に可溶化させることで内用液と注射薬がようやく日本でも開発された。内用液はカプセル薬に比べ消化管からの吸収性が改善され，注射薬は2日間のLoading dose（400 mg分2/日）により ...
河野, 茂
core  

Observational study of the recent efficacy and economy of itraconazole vs. voriconazole in perioperative pulmonary aspergillosis

Frontiers in Surgery
BackgroundAntifungal therapy is a common treatment option for pulmonary aspergillosis, but its use to prevent recurrence and relieve symptoms in patients with pulmonary aspergillosis remains controversial.
Peng Chen, Xiao Zhang, Xinzhe Zheng, Yang Tang, Yongxiang Song, Gang Xu, Xixian Ke, Cheng Chen   +7 more
doaj   +1 more source

Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry [PDF]

, 2010
Background: Posaconazole is a novel antifungal drug for oral application intended especially for therapy of invasive mycoses. Due to variable gastrointestinal absorption, adverse side effects, and suspected drug-drug interactions, therapeutic drug ...
Michael Vogeser, Karl J. Lackner, Burghardt, Stephan, Lackner, Karl J., Vogelsberger, Rita, Krueger, Ralf, Stephan Burghardt, Vogeser, Michael, Rita Vogelsberger, Ralf Krüger   +9 more
core   +1 more source