Results 1 to 10 of about 14,886 (208)

Targeting Mitochondrial Stress Responses: Terbinafine and Miglustat as Novel Lifespan and Healthspan Modulators. [PDF]

Aging Cell
Terbinafine and miglustat are mitohormetic compounds that extend lifespan and healthspan. In C. elegans, these FDA‐approved drugs engage both ATFS‐1 and DAF‐16, highlighting a stress‐dependent coordination between mitochondrial and IIS pathways distinct from canonical IIS activation, relevant for healthy aging.
Lalou A, Daskalaki I, Gkikas I, Rodríguez-López S, Morel JD, Benegiamo G, Faure A, Gao AW, Barmaz J, Wang Q, Li TY, Gao F, Broustail D, Schoonjans K, D'Angelo G, Auwerx J.   +15 more
europepmc   +2 more sources

Variational Inference for Generalized Linear Mixed Models Using Partially Noncentered Parametrizations

, 2013
The effects of different parametrizations on the convergence of Bayesian computational algorithms for hierarchical models are well explored. Techniques such as centering, noncentering and partial noncentering can be used to accelerate convergence in MCMC
Nott, David J., Tan, Linda S. L.
core   +1 more source

Antifungal therapy in birds : old drugs in a new jacket [PDF]

, 2018
Antonissen, Gunther, Martel, An
core   +2 more sources

Risk of serious skin disorders among users of oral antifungals: a population-based study [PDF]

, 2002
Jordi Castellsague, Luís-Alberto García-Rodríguez, Alberto Duque, Susana Pérez, LA García Rodríguez, H Jick, H Jick, NE Breslow, STATA, JC Roujeau, B Rzany   +10 more
core   +1 more source

Terbinafine-induced liver injury with isolated serum alkaline phosphatase elevation: A case report and literature review. [PDF]

J Int Med Res
Liu YH, Guo Y, Xu H, Feng H, Pan F.
europepmc   +1 more source

Global Emergence of <i>Trichophyton mentagrophytes</i> ITS Genotype VIII (<i>Trichophyton indotineae</i>): A Scoping Review of Epidemiology, Clinical Features, and Antifungal Resistance, 2019-2025. [PDF]

Infect Drug Resist
Gupta AK, Liddy A, Wang T, Kaplan B, Shemer A, Talukder M.   +5 more
europepmc   +1 more source

The Evolving Landscape of Dermatophytosis in the UAE: Trichophyton indotineae and Related Genotypes. [PDF]

Mycoses
Vanam HP, Ghazawi A, Aljneibi D, Khan M, Jabeen F, Alsuwaidi AR, Thomsen J, AlBataineh M, Weber S, Gibas C, Wiederhold NP, Al Dhaheri F.   +11 more
europepmc   +1 more source

Bioanalytical UHPLC-MS/MS Method for Quantification of Terbinafine in Ungual Delivery Studies. [PDF]

Biomed Chromatogr
Rossier B, Varesio E, Allémann E, Kalia YN.   +3 more
europepmc   +1 more source

Rising antifungal resistance in <i>Trichophyton</i> species-the bleak future for treatment of dermatomycosis? [PDF]

Front Microbiol
Burmester A, Tittelbach J, Uhrlass S, Nenoff P, Fabri M, Wiegand C.   +5 more
europepmc   +1 more source

A Chinese warning: Terbinafine-resistant Trichophyton indotineae, a global dermatological challenge. [PDF]

J Eur Acad Dermatol Venereol
Zhou X, de Hoog S.
europepmc   +1 more source