We use here two genomic screens in an attempt to understand the mode of action and resistance mechanism of terbinafine, an antifungal contemplated as a potential drug against the parasite Leishmania.
Jade-Éva Potvin +5 more
doaj +1 more source
Terbinafine and antidepressants: Potential risk of medication induced mania
Introduction Mood destabilization and induced manic episodes are well-known phenomenon under antidepressant medications. However, even with a cautious introduction of antidepressants, it’s important to be aware of possible pharmacological interactions.
P. Barbosa +3 more
doaj +1 more source
The yeast P5 type ATPase, Spf1, regulates manganese transport into the endoplasmic reticulum [PDF]
The endoplasmic reticulum (ER) is a large, multifunctional and essential organelle. Despite intense research, the function of more than a third of ER proteins remains unknown even in the well-studied model organism Saccharomyces cerevisiae.
A Chesi +95 more
core +11 more sources
Green Microalgae Strain Improvement for the Production of Sterols and Squalene
Sterols and squalene are essential biomolecules required for the homeostasis of eukaryotic membrane permeability and fluidity. Both compounds have beneficial effects on human health. As the current sources of sterols and squalene are plant and shark oils,
Supakorn Potijun +4 more
doaj +1 more source
Combining derivative and synchronous approaches for simultaneous spectrofluorimetric determination of terbinafine and itraconazole [PDF]
In this study, determination of terbinafine and itraconazole down to biological concentration level has been carried out. The determination is based on increasing the selectivity of the spectrofluorimetric technique by combining both derivative and ...
Heba Elmansi +3 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Background:Tinea pedis (athletic foot) is the most common dermatophytic fungal infection of the body. It may last for a short or long time and may recur after treatment.
Araz Hasan Mohammed, +1 more
doaj +1 more source
Antimicrobial susceptibility testing of dermatophytes - Comparison of the agar macrodilution and broth microdilution tests [PDF]
Fifty dermatophyte strains, recently obtained from clinical material, belonging to 4 different species were examined for their susceptibility to 5 systemic or topical antimycotic agents using both an agar macrodilution and a broth microdilution test ...
Abeck, Dietrich +4 more
core +1 more source
Antifungal Susceptibility Pattern of Non - Dermatophytic Fungi Causing Onychomycosis
Introduction: Non-dermatophytic molds (NDM) are filamentous fungi or yeast, commonly found in nature as saprophytes and plant pathogens. The incidence of onychomycosis due to NDM is 1.45 – 16.6%.
Apurva Kaushal +5 more
doaj +3 more sources
Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]
Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian +2 more
core +1 more source

