Results 31 to 40 of about 15,127 (212)

Skin Permeability of Different Terbinafine Hydrochloride Formulations

European Journal of Inflammation, 2008
The objectives of the study are to determine the in vitro permeability of different terbinafine hydrochloride formulations through human skin and to measure the respective concentrations of each formulation within the exposed skin tissue.
E. Pretorius, P.J.D. Bouic, Q. Thebus, W. Kriek   +3 more
doaj   +1 more source

Effect of Terbinafine on the Pharmacokinetics of Cyclosporin in Humans [PDF]

, 1994
Cyclosporin is largely metabolized by hepatic cytochrome P450 enzymes, and azole drugs that inhibit cytochrome P450 may precipitate cyclosporin toxicity. The allylamine terbinafine binds to a small subfraction of hepatic cytochrome P450 in type I fashion,
Blankers, Matthijs, Busschbach, Jan J.V., Dekker, Jack J.M., Kikkert, Martijn J., Laurenssen, Elisabeth M.P., Luyten, Patrick, Peen, Jaap, Soons, Mirjam B.J., van Broekhuyzen, Anna J., van Dam, Anne Marie, Westra, Dieuwertje   +10 more
core   +2 more sources

Two Strategies to Enhance Ungual Drug Permeation from UV-cured Films: Incomplete Polymerisation to Increase Drug Release and Incorporation of Chemical Enhancers [PDF]

, 2018
UV-curable gels, which polymerise into long-lasting films upon exposure to UVA, have been identified as potential topical drug carriers for the treatment of nail diseases.
Bardes, Josep, Hilton, Stephen, Kerai, Laxmi, Murdan, Sudaxshina   +3 more
core   +3 more sources

Efficacy and safety of terbinafine 500 mg once daily in patients with dermatophytosis

Indian Journal of Dermatology, 2017
Introduction: Dermatophytosis are the most common fungal infections globally. Terbinafine is considered to have good potency against dermatophytes, but resistance to terbinafine is on the rise.
P Ravindra Babu, A J S Pravin, Gaurav Deshmukh, Dhiraj Dhoot, Aniket Samant, Bhavesh Kotak   +5 more
doaj   +1 more source

Investigation on utility of some novel terpenes on transungual delivery of terbinafine for the management of onychomycosis

Dermatology Practical & Conceptual, 2022
Introduction: Onychomycosis is a fungal disorder of the nail which afflicts 5% of the population worldwide. The disease is strenuous to cure as it is chronic, hard to eliminate and tends to recur. Topical therapy is at the forefront for the treatment of
Isha Gupta, Syeda Nashvia Adin, Mohd Aqil, Mohd Mujeeb, Yasmin Sultana   +4 more
doaj   +1 more source

In vitro activities of amphotericin B, terbinafine, and azole drugs against clinical and environmental isolates of apergillus terreus Sensu Stricto [PDF]

, 2015
The antifungal susceptibilities of 40 clinical and environmental isolates of A. terreus sensu stricto to amphotericin B, terbinafine, itraconazole, and voriconazole were determined in accordance with CLSI document M38-A2.
Cattana, Maria Emilia, Fernández, Mariana Soledad, Giusiano, Gustavo Emilio, Iovannitti, Cristina A., Lass Flörl, Cornelia, Rojas, Florencia Dinorah, Sosa, Maria de Los Angeles   +6 more
core   +1 more source

In vitro Activity of Allicin Alone and in Combination With Antifungal Drugs Against Microsporum canis Isolated From Patients With Tinea Capitis

Frontiers in Medicine, 2021
The checkerboard broth method based on the Clinical and Laboratory Standards Institute M38-A3 document was used in this study to evaluate the in vitro activity of allicin alone and in combination with the antifungal drugs (griseofulvin, fluconazole ...
Ya Bin Zhou, Yuan Yuan Xiao, Jin Jing Chao, Lin Ma   +3 more
doaj   +1 more source

Systemic antifungal therapy for tinea capitis in children:An abridged Cochrane Review [PDF]

, 2017
BackgroundThe comparative efficacy and safety profiles of systemic antifungal drugs for tinea capitis in children remain unclear.ObjectiveWe sought to assess the effects of systemic antifungal drugs for tinea capitis in children.MethodsWe used standard ...
Bennett, Cathy, Chen, Xiaomei, González, Urbà, Hua, Xia, Jiang, Xia, Lin, Xiufang, Xue, Siliang, Yang, Ming, Zhang, Min   +8 more
core   +1 more source

Modulation of yeast Erg1 expression and terbinafine susceptibility by iron bioavailability

Microbial Biotechnology, 2022
Ergosterol is a specific sterol component of yeast and fungal membranes. Its biosynthesis is one of the most effective targets for antifungal treatments.
Tania Jordá, Ana Martínez‐Martín, María Teresa Martínez‐Pastor, Sergi Puig   +3 more
doaj   +1 more source

The Influence of Oral Terbinafine on Gut Fungal Microbiome Composition and Microbial Translocation in People Living with HIV Treated for Onychomycosis

Journal of Fungi, 2023
People living with HIV (PLWH) display altered gut epithelium that allows for the translocation of microbial products, contributing to systemic immune activation.
Jing Ouyang, Jiangyu Yan, Xin Zhou, Stéphane Isnard, Shengquan Tang, Cecilia T. Costiniuk, Yaling Chen, Jean-Pierre Routy, Yaokai Chen   +8 more
doaj   +1 more source