Results 31 to 40 of about 10,703 (208)

Update on terbinafine with a focus on dermatophytoses

, 2009
Jason G Newland1,3, Susan M Abdel-Rahman2,3Divisions of Infectious Diseases1 and Clinical Pharmacology and Medical Toxicology2, Children’s Mercy Hospitals and Clinics, Kansas City, MO, USA; 3Department of Pediatrics, University of Missouri ...
Jason G Newland, Susan M Abdel-Rahman, null Newland, Susan Abdel-Rahman   +3 more
core   +1 more source

Terbinafine versus itraconazole: a long-term, randomized, double-blind, clinical trial in chronic pulmonary aspergillosis. A pilote study [PDF]

Journal of Health and Social Sciences, 2016
Background: The frequency of pulmonary aspergillosis has been increasing for decades. Standard oral treatment is associated with tolerability problems and interactions with commonly used medications.
Gianfranco Schiraldi, Salvatore Lo Cicero, Claudio Rossetti, Delia Colombo, Michele Chiericozzi, Elvana Kola, Luigi Allegra   +6 more
doaj   +1 more source

Synergistic effect of terbinafine and amphotericin B in killing Fonsecaea nubica in vitro and in vivo

Revista do Instituto de Medicina Tropical de São Paulo
Chromoblastomycosis is a chronic fungal infection. Itraconazole and terbinafine are the most recommended antifungal drugs for chromoblastomycosis, while amphotericin B is not usually recommended.
Jing Zhang, Xiaoyan Wu, Meirong Li, Jiamin Huang, Songchao Yin, Huaiqiu Huang, Chun Lu, Liyan Xi   +7 more
doaj   +1 more source

Fungal Translocation Marker in People Living with HIV Needing Treatment for Onychomycosis: A Protocol for the Prospective Pilot Study

Infectious Diseases & Immunity, 2022
. Increased microbial translocation and chronic immune activation are two critical problems for people living with HIV (PLWH) in the antiretroviral therapy (ART) era.
Yaling Chen, Jing Ouyang, Stéphane Isnard, Cecilia T. Costiniuk, Jiangyu Yan, Xin Zhou, Jean-Pierre Routy, Yaokai Chen, Wei Zhao   +8 more
doaj   +1 more source

Employment of terbinafine against Pneumocystis carinii infection in rat models

, 1996
The anti-Pneumocystis carinii response of terbinafine together with that of three other compounds, trimethoprim sulphamethoxazole (TMP-SMX), atovaquone (ATQ) and albendazole (ALE), has been investigated in immunosuppressed Sprague-Dawley rats with ...
D. Colombo, T. Sechi, C. Contini, CANIPARI, Rita, R. Cultrera, E. Prini, ANGELICI, Elena   +6 more
core   +1 more source

Allergic Maculo-Papular Exanthema Due To Terbinafine [PDF]

, 2017
We report on a 76-year-old male patient who developed a maculopapular generalised exanthema due to terbinafine. Prick test was negative; patch test revealed a positive reaction after 48 h confirming the delayed-type allergic reaction.
Koch, André, Wollina, Uwe, Tchernev, Georgi   +2 more
core   +1 more source

Evaluation of efficacy and safety of topical 1% terbinafine versus topical 2% sertaconazole in patients with tinea cruris – A randomized controlled trial

National Journal of Physiology, Pharmacy and Pharmacology, 2021
Background: Dermatophyte infections are very common and they manifest as tinea corporis/cruris. Among the various topical antifungal drugs available, the first option being terbinafine and new generation azoles as sertaconazole professes superior ...
Meghana D, Laxminarayana Kamath, Revathi T N   +2 more
doaj   +1 more source

Involvement of the Jnk Activation in Terbinafine-Induced P21 up- Regulation and DNA Synthesis Inhibition in Human Vascular Endothelial Cells

, 2010
Previously, we demonstrated that the extracellular signal- regulated kinase (ERK)-mediated pathway contributes to the terbinafine (TB)-induced increases of p21 and p53 protein level as well as decrease of DNA synthesis in human umbilical venous ...
HSU, SUNG-PO;HO, PEI-YIN;LIANG, YU-CHIH;HO, YUAN-SOON;LEE, WEN-SEN, 徐松柏;何蓓茵;梁有志;何元順;李文森   +1 more
core   +1 more source

Detailed Mechanism of Squalene Epoxidase Inhibition by Terbinafine

, 2016
Squalene epoxidase (SE) is a key flavin adenine dinucleotide (FAD)-dependent enzyme of ergosterol and cholesterol biosynthetic pathways and an attractive potential target for drugs used to inhibit the growth of pathogenic fungi or to lower cholesterol ...
Piotr Stepniak (2228593), Krzysztof Ginalski (8940), Leszek Rychlewski (4282), Marcin Nowosielski (2228587), Dariusz M. Plewczynski (2228590), Michal Lazniewski (1561627), Lucjan S. Wyrwicz (2228584), Marcin Hoffmann (1492771)   +7 more
core   +4 more sources

Generalized pustular eruptions due to terbinafine

, 2011
Terbinafine, a widely used antifungal agent, may rarely cause cutaneous side effects with an incidence of 2.7%. Generalized pustular eruptions are quite uncommon but severe adverse cutaneous reactions of terbinafine have been reported.
Karaca, Nezih, Bengu Gerceker Turk, Alican Kazandi, Ertekin, Banu, Kandiloglu, Gulsen, Turk, Bengu Gerceker, Banu Ertekin, Nezih Karaca, Ertam, Ilgen, Gunseli Ozturk, Ozturk, Gunseli, Gulsen Kandiloglu, Ilgen Ertam, Isil Kilinc Karaarslan, Karaarslan, Isil Kilinc, Kazandi, Alican   +15 more
core   +1 more source