Results 11 to 20 of about 15,127 (212)

The Global Antifungal Susceptibility Epidemiology of Trichophyton indotineae Indicating Voriconazole as an Alternative Therapy for Recalcitrant Dermatophytosis. [PDF]

Mycoses
ABSTRACT Background The emergence of Trichophyton indotineae as a multidrug‐resistant dermatophyte has challenged conventional therapeutic approaches for dermatophytosis, leading to a significant therapeutic dilemma. The absence of formal epidemiological cutoff values (ECVs) under the Clinical and Laboratory Standards Institute (CLSI) framework has led
Song G, Xie W, She X, Liu W, Li X, Liang G.   +5 more
europepmc   +2 more sources

Increasing Terbinafine Resistance in Danish Trichophyton Isolates 2019–2020

Journal of Fungi, 2022
Terbinafine resistance in Trichophyton species has emerged and appears to be increasing. A new EUCAST susceptibility testing method and tentative ECOFFs were recently proposed for Trichophyton.
Karen Marie Thyssen Astvad, Rasmus Krøger Hare, Karin Meinike Jørgensen, Ditte Marie Lindhardt Saunte, Philip Kjettinge Thomsen, Maiken Cavling Arendrup   +5 more
doaj   +1 more source

Investigating the interaction of terbinafine with xanthenes dye for its feasible determination applying the resonance Rayleigh scattering technique [PDF]

Royal Society Open Science, 2021
Terbinafine hydrochloride is a potent antifungal drug indicated for oral and topical treatment of mycoses. A resonance Rayleigh scattering (RRS) method was developed for the determination of terbinafine hydrochloride through a feasible complexation ...
Mohamed A. Abdel-Lateef, Sayed M. Derayea, Deena A. M. Nour El-Deen, Albandary Almahri, Mohamed Oraby   +4 more
doaj   +1 more source

Terbinafine and antidepressants: Potential risk of medication induced mania

European Psychiatry, 2021
Introduction Mood destabilization and induced manic episodes are well-known phenomenon under antidepressant medications. However, even with a cautious introduction of antidepressants, it’s important to be aware of possible pharmacological interactions.
P. Barbosa, O. Nombora, J. Monteiro, L. Ribeiro   +3 more
doaj   +1 more source

Increased copy number of the target gene squalene monooxygenase as the main resistance mechanism to terbinafine in Leishmania infantum

International Journal for Parasitology: Drugs and Drug Resistance, 2023
We use here two genomic screens in an attempt to understand the mode of action and resistance mechanism of terbinafine, an antifungal contemplated as a potential drug against the parasite Leishmania.
Jade-Éva Potvin, Fereshteh Fani, Marine Queffeulou, Élodie Gazanion, Philippe Leprohon, Marc Ouellette   +5 more
doaj   +1 more source

The yeast P5 type ATPase, Spf1, regulates manganese transport into the endoplasmic reticulum [PDF]

, 2013
The endoplasmic reticulum (ER) is a large, multifunctional and essential organelle. Despite intense research, the function of more than a third of ER proteins remains unknown even in the well-studied model organism Saccharomyces cerevisiae.
A Chesi, A Samali, A Szkopińska, AB Bowman, AD Gitler, AH Futerman, Alaa Abdul-Sada, Anthony H. Futerman, AR Reddi, C Janke, C Onyewu, C Suzuki, C Suzuki, CB Brachmann, CC Paulusma, CD Davis, D Berchtold, D Lockshon, D Mandal, D Sorger, DJ Tipper, DK Breslow, E Losev, E Papanikou, E Sammels, E Wiederhold, EH Hettema, F Sherman, Fischl, Frances M. Platt, G Giaever, GA Castillon, GA Castillon, Giuseppe Condomitti, GK Voeltz, GR Corradi, H Yoshida, Howard Riezman, I Braakman, Isabelle Riezman, J Ko, J Meldolesi, J Shima, JA Sullivan, JK Pittman, JM De Freitas, K Araki, K Krumpe, KB Axelsen, LJ Wuestehube, LS Weingarten, LT Jensen, M Fujita, M Fujita, M Fujita, M North, M Schuldiner, M Schuldiner, Maya Schuldiner, MC Jonikas, MS Bae-Lee, Márton Megyeri, N Rimon, Nitzan Rimon, NP Mira, Oscar C. W. Chen, P Estrada de Martin, P Fagone, PJ Schultheis, PL Pedersen, RC Dickson, RC Dickson, RD Gietz, S Ichikawa, S Vashist, S-X Tan, SA Heidler, SC Dos Santos, SL Hansen, SR Cronin, SR Cronin, Stephen W. Michnick, TP Levine, U Loizides-Mangold, Ursula Loizides-Mangold, V Cerantola, V V Kushnirov, VC Culotta, W Kühlbrandt, X Tang, X Zhou, XF Liu, XL Guan, Y Chen, YD Lobsanov, Yifat Cohen   +95 more
core   +11 more sources

Combining derivative and synchronous approaches for simultaneous spectrofluorimetric determination of terbinafine and itraconazole [PDF]

Royal Society Open Science, 2020
In this study, determination of terbinafine and itraconazole down to biological concentration level has been carried out. The determination is based on increasing the selectivity of the spectrofluorimetric technique by combining both derivative and ...
Heba Elmansi, Aya Roshdy, Shereen Shalan, Amina El-Brashy   +3 more
doaj   +1 more source

Green Microalgae Strain Improvement for the Production of Sterols and Squalene

Plants, 2021
Sterols and squalene are essential biomolecules required for the homeostasis of eukaryotic membrane permeability and fluidity. Both compounds have beneficial effects on human health. As the current sources of sterols and squalene are plant and shark oils,
Supakorn Potijun, Suparat Jaingam, Nuttha Sanevas, Srunya Vajrodaya, Anchalee Sirikhachornkit   +4 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]

, 2008
Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian, Schäfer-Korting, Monika, Schöllmann, C.   +2 more
core   +1 more source